FB2026_02 , released June 18, 2026
Allele: Dmel\dlS70A
Open Close
General Information
Symbol
Dmel\dlS70A
Species
D. melanogaster
Name
FlyBase ID
FBal0095462
Feature type
allele
Associated gene
Dmel\dl
Associated Insertion(s)
Carried in Construct
P{dlS70A}
Key Links
Transgenic product class
missense_variant
(Drier et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Drier et al., 1999)
Mutagen
in vitro construct
(Drier et al., 1999)
Progenitor genotype
dl+mWT
(Drier et al., 1999)
Carried in construct
P{dlS70A}
Cytology
Description

Amino acid replacement S70A, in the Rel homology region of the protein.

(Drier et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
dl
Encoded product / tool
dl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      One copy of dlS70A does not rescue embryos derived from dl null mothers to hatching, while two copies of dlS70A supports a low level of hatching of embryos derived from dl null mothers. Embryos derived from dl null mothers carrying one copy of dlS70A are weakly dorsalised, while those embryos derived from dl null mothers carrying two copies of dlS70A have wild-type cuticles. Embryos derived from dl1 cact7 mothers carrying dlS70A are strongly ventralised and do not hatch.

      (Drier et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      dlS70A partially rescues dlunspecified

      (Drier et al., 1999)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      dlS70A
      Name Synonyms
      Secondary FlyBase IDs
        References (1)