FlyBase Allele Report: Dmel\Rbf[11]

General Information

Symbol

Dmel\Rbf¹¹

Species

D. melanogaster

Name

FlyBase ID

FBal0095622

Feature type

allele

Associated gene

Dmel\Rbf

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Du and Dyson, 1999)

Progenitor genotype

Rbf^38a

(Du and Dyson, 1999)

Rbf^15a

(Du and Dyson, 1999)

Rbf^120a

(Du and Dyson, 1999)

Cytology

Description

Imprecise excision of the P{CaSpeR} element, resulting in complete deletion of the Rbf coding sequence.

(Du and Dyson, 1999)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased occurrence of cell division | larval stage (with Rbf^120a)

(Brumby et al., 2002)

lethal | recessive

(Du and Dyson, 1999)

sterile (with Rbf^120a)

(Brumby et al., 2002)

viable (with Rbf^120a)

(Brumby et al., 2002)

Phenotype Manifest In

egg chorion (with Rbf^120a)

(Brumby et al., 2002)

eye (with Rbf^120a)

(Brumby et al., 2002)

eye disc (with Rbf^120a)

(Brumby et al., 2002)

follicle cell & cell cycle (with Rbf^120a)

(Brumby et al., 2002)

S phase | ectopic & eye disc | posterior (with Rbf^120a)

(Brumby et al., 2002)

Detailed Description

Statement

Reference

Rbf¹¹/Rbf^120a eye discs have a severe disruption in the post-morphogenetic furrow S phase band, but have excessive S phases in the posterior region. Despite this disruption, the adult eye phenotype is only mildly disorganised.

(Brumby et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Rbf¹¹ is a suppressor of sterile | recessive | female phenotype of Cdk4³

(Meyer et al., 2000)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Rbf^120a/Rbf¹¹ has S phase | ectopic & eye disc | posterior phenotype, non-enhanceable by brm^25S14/mor^35S1

(Brumby et al., 2002)

Rbf^120a/Rbf¹¹ has eye disc phenotype, non-enhanceable by brm^25S14/mor^35S1

(Brumby et al., 2002)

Rbf^120a/Rbf¹¹ has eye phenotype, non-enhanceable by brm^25S14/mor^35S1

(Brumby et al., 2002)

NOT suppressed by

Statement

Reference

Rbf^120a/Rbf¹¹ has eye disc phenotype, non-suppressible by brm^25S14/mor^35S1

(Brumby et al., 2002)

Rbf^120a/Rbf¹¹ has eye phenotype, non-suppressible by brm^25S14/mor^35S1

(Brumby et al., 2002)

Rbf^120a/Rbf¹¹ has S phase | ectopic & eye disc | posterior phenotype, non-suppressible by brm^25S14/mor^35S1

(Brumby et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Rbf¹¹ does not genetically interact with vri^unspecified in double heterozygous combination.

(Szuplewski et al., 2003)

The addition of brm^25S14 and mor^35S1 to Rbf^120a/Rbf¹¹ animals has no effect on eye disc and eye phenotypes.

(Brumby et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Rbf¹⁴/Rbf¹¹ is rescued by Rbf^hs.PD

(Du and Dyson, 1999)

Rbf¹¹ is rescued by Rbf^hs.PD

(Du and Dyson, 1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

"Rbf^15a" was stated as tentative. "Rbf^38a" was stated as tentative. "Rbf^120a" was stated as tentative.

(Du and Dyson, 1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

RBF¹¹

(Meyer et al., 2000)

Rbf¹¹

(Dominado et al., 2016)

rbf¹¹

(Szuplewski et al., 2003, Du, 2000, Du and Dyson, 1999)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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