FlyBase Allele Report: Dmel\brm[25S14]

General Information

Symbol

Dmel\brm^25S14

Species

D. melanogaster

Name

FlyBase ID

FBal0147253

Feature type

allele

Associated gene

Dmel\brm

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

X ray

(Brumby et al., 2004, Brumby et al., 2002)

ethyl methanesulfonate

(Brumby et al., 2004)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage | recessive

(Brumby et al., 2004)

some die during embryonic stage | recessive

(Brumby et al., 2004)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

brm^25S14 is an enhancer of eye phenotype of BacA\p35^GMR.PH, CycE^UAS.cRa, Scer\GAL4^GMR.PF

(Brumby et al., 2002)

NOT Enhancer of

Statement

Reference

brm^25S14/mor^35S1 is a non-enhancer of S phase | ectopic & eye disc | posterior phenotype of Rbf^120a/Rbf¹¹

(Brumby et al., 2002)

brm^25S14/mor^35S1 is a non-enhancer of eye disc phenotype of Rbf^120a/Rbf¹¹

(Brumby et al., 2002)

brm^25S14/mor^35S1 is a non-enhancer of eye phenotype of Rbf^120a/Rbf¹¹

(Brumby et al., 2002)

Suppressor of

Statement

Reference

brm^25S14/brm[+] is a suppressor of eye phenotype of CycE^JP

(Brumby et al., 2004)

brm^25S14 is a suppressor of eye phenotype of CycE^JP

(Brumby et al., 2002)

NOT Suppressor of

Statement

Reference

brm^25S14/mor^35S1 is a non-suppressor of eye disc phenotype of Rbf^120a/Rbf¹¹

(Brumby et al., 2002)

brm^25S14/mor^35S1 is a non-suppressor of eye phenotype of Rbf^120a/Rbf¹¹

(Brumby et al., 2002)

brm^25S14/mor^35S1 is a non-suppressor of S phase | ectopic & eye disc | posterior phenotype of Rbf^120a/Rbf¹¹

(Brumby et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Suppresses the CycE^JP rough eye phenotype. CycE^Scer\UAS.cRa when driven by Scer\GAL4^GMR.PF causes eye overgrowth and rough eye phenotype. Addition of brm^25S14 enhances this phenotype. The addition of brm^25S14 and mor^35S1 to Rbf^120a/Rbf¹¹ animals has no effect on eye disc and eye phenotypes.

(Brumby et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

brm^unspecified

(Brumby et al., 2004)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

"X ray" was stated as tentative. "ethyl methanesulfonate" was stated as tentative.

(Brumby et al., 2004)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

25S14

(Brumby et al., 2004)

brm^25S14

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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