FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Mtpβ00628
Open Close
General Information
Symbol
Dmel\Mtpβ00628
Species
D. melanogaster
Name
FlyBase ID
FBal0097090
Feature type
allele
Associated gene
Dmel\Mtpβ
Associated Insertion(s)
P{PZ}ken00628
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Kolhekar et al., 1997)
Progenitor genotype
Associated Insertion(s)
P{PZ}ken00628
Cytology
Description

P{PZ} insertion in the intergenic region between ken and Thiolase (at position 16,670-16,677, coordinates according to EMBL accession record AB010261).

(Lukacsovich et al., 1999)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      Thiolase[+]/Mtpβ00628 is a non-enhancer of visible | heat sensitive phenotype of peb1

      (Wilk et al., 2004)
      NOT Suppressor of
      Statement
      Reference

      Thiolase[+]/Mtpβ00628 is a non-suppressor of visible | heat sensitive phenotype of peb1

      (Wilk et al., 2004)
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      Thiolase[+]/Mtpβ00628 is a non-enhancer of eye | heat sensitive phenotype of peb1

      (Wilk et al., 2004)
      NOT Suppressor of
      Statement
      Reference

      Thiolase[+]/Mtpβ00628 is a non-suppressor of eye | heat sensitive phenotype of peb1

      (Wilk et al., 2004)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Mtpβk09828

      (BDGP Project Members, 1994-1999)
      Comments

      The P{PZ}ken00628 insertion is in the intergenic region between the divergently transcribed ken and Thiolase genes. P{PZ}ken00628 fails to complement P{PZ}ken02970 (an insertion in the ken coding region) and P{lacW}Thiolasek09828, but P{PZ}ken02970 and P{lacW}Thiolasek09828 complement each other. This indicates that the P{PZ}ken00628 insertion is affecting both the ken and Thiolase genes and that the P{lacW}Thiolasek09828 insertion is a mutation in the Thiolase gene.

      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      This allele was listed in the BDGP database as a lethal or sterile line during the period 1994-1999, but was discarded from the gene disruption project prior to the summary publication (FBrf0111489). Reasons for excluding lines from the collection described in FBrf0111489 include presence of more than one P insertion on the mutant chromosome, separation of lethality (or sterility) from the location of the insertion, and loss of lethality (or sterility) from the stock. Further information is available from http://www.fruitfly.org/bfd/ and from Dr. Spradling (spradling@mail1.ciwemb.edu).

      The P{PZ}ken00628 insertion may affect the Thiolase gene as well as the ken gene.

      (Lukacsovich et al., 1999)

      Complements Phmk07623.

      (Kolhekar et al., 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Mtpβ00628
      P942
      (Kolhekar et al., 1997)
      Thiolase00628
      l(2)00628
      (Lukacsovich et al., 1999)
      l(2)0062800628
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0007950
      References (6)