FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Rbp9Δ1
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General Information
Symbol
Dmel\Rbp9Δ1
Species
D. melanogaster
Name
FlyBase ID
FBal0097180
Feature type
allele
Associated gene
Dmel\Rbp9
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Kim-Ha et al., 1999)
Mutagen
Delta2-3 transposase
(Kim-Ha, 2000, Kim-Ha et al., 1999)
Progenitor genotype
P{lacW}Rbp9P2775
(Kim-Ha, 2000)
Rbp9P2775
(Kim-Ha et al., 1999)
Cytology
Description

Deletion from approximately nucleotides 3400-7132, removing the Rbp9 P3 promoter and a 0.45kb segment of the coding region (encoding the N-terminal 150 amino acids) including the translational initiation codon.

(Kim-Ha et al., 1999)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2L:2,958,012..2,961,745 [+]
Comment:

Approximate location of deletion.

(Kim-Ha et al., 1999)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  nervous system disease
      modeled by AtpαCJ5
      (Talsma et al., 2014)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ovarioles of mutant females are filled with egg chambers with abnormal numbers of cystocytes that never develop beyond a stage 6 egg chamber. Germaria are enlarged. In a few cases the ovarioles are devoid of egg chambers. As the flies age, the underdeveloped egg chambers become filled with numerous small cells (the "tumerous bag" phenotype). Fusomes in mutant germaria are malformed.

      (Kim-Ha et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      Rbp9Δ1 is a non-enhancer of female germline cell phenotype of Rbfox1f02600/Rbfox1e03440

      (Tastan et al., 2010)
      NOT Suppressor of
      Statement
      Reference

      Rbp9Δ1 is a non-suppressor of female germline cell phenotype of Rbfox1f02600/Rbfox1e03440

      (Tastan et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Rbp9Δ1 is rescued by Rbp9+t17.1

      (Kim-Ha et al., 1999)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Rbp9Delta1
      (Marcogliese et al., 2017)
      Rbp9Δ1
      (Kim-Ha, 2000)
      rbp9Δ1
      (Tastan et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)