FB2026_02 , released June 18, 2026
Allele: Dmel\Ras85DQ13.UAS
Open Close
General Information
Symbol
Dmel\Ras85DQ13.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0097183
Feature type
allele
Associated gene
Dmel\Ras85D
Associated Insertion(s)
Carried in Construct
P{UAS-Ras85D.Q13}
Also Known As
UAS-Ras1Q13(II)B
Key Links
Transgenic product class
missense_variant
(Harden et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Harden et al., 1999)
Mutagen
in vitro construct
(Harden et al., 1999)
Progenitor genotype
Carried in construct
P{UAS-Ras85D.Q13}
Cytology
Description

A constitutively active form of Ras85D is expressed under the control of UASt regulatory sequences.

(Harden et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Ras85D
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  cancer
      CEA
      (Tamamouna et al., 2021)
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      model of  cancer
      is ameliorated by CatUAS.cAa
      (Tamamouna et al., 2021)
      is ameliorated by Sod1UAS.cAa
      (Tamamouna et al., 2021)
      is ameliorated by btlDN.UAS
      (Tamamouna et al., 2021)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Ras85DQ13.Scer\UAS under the control of Scer\GAL4repo in embryos does not disrupt peripheral glial or neuronal development compared to wild-type embryos.

      (Sepp and Auld, 2003)

      Expression of Ras85DQ13.Scer\UAS driven by Scer\GAL4332.3 does not affect either the dorsal cuticle or amnioserosa morphology.

      (Harden et al., 2002)

      Expression of Ras85DQ13.Scer\UAS using Scer\GAL4ptc-559.1 results in a high frequency of defects in the dorsal cuticle.

      (Harden et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ras85DQ13.Scer\UAS
      Ras85DQ13.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (4)