FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\DabUAS.cWa
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General Information
Symbol
Dmel\DabUAS.cWa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Wills
FlyBase ID
FBal0097372
Feature type
allele
Associated gene
Dmel\Dab
Associated Insertion(s)
Carried in Construct
P{UAS-Dab.W}
Also Known As
UAS-Dab
Key Links
Transgenic product class
wild_type
(Wills et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Wills et al., 1999)
Mutagen
in vitro construct
(Wills et al., 1999)
Progenitor genotype
Carried in construct
P{UAS-Dab.W}
Cytology
Description

Dab is expressed under the control of UAS regulatory sequences.

(Wills et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Dab
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of DabScer\UAS.cWa under the control of Scer\GAL4ppk.PG results in third instar larval class IV abdominal dorsal multidendritic ddaC neurons exhibiting abnormal dendritic terminals, as compared to controls; expression under the control of Scer\GAL4221 results in no obvious dendrite morphology defects in class I abdominal dorsal multidendritic ddaD and ddaE neurons, as compared to controls.

      (Hattori et al., 2013)

      ISNb bypass phenotypes are not produced when DabScer\UAS.cWa is expressed under the control of Scer\GAL4elav.PLu.

      (Wills et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      DabUAS.cWa/Scer\GAL4elav.PU is a non-suppressor of abnormal neuroanatomy | embryonic stage phenotype of Abl2/Abl4

      (Song et al., 2010)
      Phenotype Manifest In
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The ISNb stall phenotype seen in Abl2/Abl4 embryos is not suppressed by expression of DabScer\UAS.cWa under the control of Scer\GAL4elav.PU.

      (Song et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      DabUAS.cWa/Scer\GAL4Appl.G1a rescues DabEC1

      (Kawasaki et al., 2011)
      Partially rescues

      DabUAS.cWa/Scer\GAL4elav.PU partially rescues Dab2/Dab1

      (Song et al., 2010)

      DabUAS.cWa/Scer\GAL4sca-537.4 partially rescues Dab2/Dab1

      (Song et al., 2010)
      Comments

      The DabEC1 synaptic phenotype is rescued by neural (presynaptic) expression of DabScer\UAS.cWa under the control of Scer\GAL4Appl.G1a.

      (Kawasaki et al., 2011)

      Expression of DabScer\UAS.cWa under the control of Scer\GAL4elav.PU partially rescues the ISNb stall phenotype seen in embryos lacking both maternal and zygotic Dab function (derived from Dab1/Dab2 females and having Dab1 as the paternally derived copy of Dab).

      Expression of DabScer\UAS.cWa under the control of Scer\GAL4sca-537.4 partially rescues the ISNb stall phenotype seen in embryos lacking both maternal and zygotic Dab function (derived from Dab1/Dab2 females and having Dab2 as the paternally derived copy of Dab).

      (Song et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      DabScer\UAS.cWa
      DabUAS.cWa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Wills
      (Wills et al., 1999)
      Secondary FlyBase IDs
        References (6)