FB2026_02 , released June 18, 2026
Allele: Dmel\poeP21
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General Information
Symbol
Dmel\poeP21
Species
D. melanogaster
Name
FlyBase ID
FBal0097927
Feature type
allele
Associated gene
Dmel\poe
Associated Insertion(s)
P{lacW}poeP21
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Sekelsky et al., 1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}poeP21
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant for female meiotic segregation: 3.1% X chromosome exceptions from X/X females. 1.0% 4th chromosome exceptions from X/X females. 21.4% X chromosome exceptions from X/Bal females. 9.5% 4th chromosome exceptions from X/Bal females. Axs-like mutant. Primarily affects achiasmate chromosome segregation. Only the segregation of achiasmate chromosomes is affected. Rate of X chromosome nondisjunction is two to three fold higher than that of 4th chromosome nondisjunction. X and 4th chromosome nondisjunction show a strong positive correlation. The majority of simultaneous X and 4th chromosome nondisjunction is non-homologous XX - 44 segregation. Exchange is normal.

      (Sekelsky et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      poe03420

      (Sekelsky et al., 1999)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Analysis of excision alleles indicates that both male sterility and meiotic defect are caused by the P{lacW} insert.

      (Sekelsky et al., 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mei-P21
      (Sekelsky et al., 1999)
      poeP21
      Name Synonyms
      Secondary FlyBase IDs
        References (1)