FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\RPA3G0241
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General Information
Symbol
Dmel\RPA3G0241
Species
D. melanogaster
Name
FlyBase ID
FBal0098150
Feature type
allele
Associated gene
Dmel\RPA3
Associated Insertion(s)
P{lacW}RPA3G0241
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Zhou and Luo, 2013)
Mutagen
P-element activity
(Schäfer et al., 1999.6.15)
Progenitor genotype
Associated Insertion(s)
P{lacW}RPA3G0241
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
AJ426869
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous clones in the outer proliferation center (OPC) neuroepithelium are small and composed of only a few cells. The cells retain columnar neuroepithelium cell morphology. Some of the mutant cells are extruded from the neuroepithelium and basally enter the medulla cortex. These extruded cells change morphology and become rounded or irregular in shape.

      (Zhou and Luo, 2013)

      Lethality occurs during the first and second larval instars.

      (Peter et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      Comments
      Comments

      P{lacW} not verified as causing the lethality.

      (Schäfer et al., 1999.6.15)
      External Crossreferences and Linkouts ( 1 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      RPA3G0241
      (Li et al., 2021)
      l(1)G0241
      (Peter et al., 2002)
      l(1)G0241G0241
      (Zhou and Luo, 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)