photoreceptor cell & axon
retina & cell body
bgm1/bgm1, hll1/hll1 double mutants exhibit more severe degeneration of the lamina, as assayed by holes in the optic ganglion at 18 days old, than either single mutant, and degeneration of the retina and fenestrated membrane structure was more severe in double mutants than hll1/hll1 single mutants, but not statistically different from bgm1/bgm1 single mutants. bgm1/bgm1, hll1/hll1 double mutants show retinal holes, thinning and irregularity of the fenestrated membrane between the retina and lamina, disarray of the ommatidial structure not visible in newly eclosed flies but apparent at day 20, and loss of monopolar neurons (often associated with abnormal extracellular precipitates), loss of secondary pigment cells, decreased locomotor activity to a similar degree as single mutants, a small decrease in lifespan, evidence of increased lipid accumulation in the larval gut, but not in the adult eye, as compared to wild type. These mutants do not exhibit a rough eye phenotype.