FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SNF4AγS005042
Open Close
General Information
Symbol
Dmel\SNF4AγS005042
Species
D. melanogaster
Name
FlyBase ID
FBal0100205
Feature type
allele
Associated gene
Dmel\SNF4Aγ
Associated Insertion(s)
P{lacW}SNF4AγS005042
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Deak et al., 1997)
P-element activity
(Szeged Stock Center, 1998-)
Progenitor genotype
Associated Insertion(s)
P{lacW}SNF4AγS005042
Cytology
Description

Insertion 29bp upstream of the transcription start site of the SNF4Aγ-RL transcript.

(Lippai et al., 2008)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Fat body cells of homozygous late third instar larvae are essentially unable to form autophagosomes, lysosomes or autolysosomes. The number and size of lipid droplets is normal in these cells.

      Mutant third larval instar fat body cells do not form autophagic structures in response to 20-hydroxyecdysone or in response to amino acid deprivation for four hours in contrast to wild-type control cells.

      SNF4AγS005042/SNF4AγS012719 animals die before pupariation.

      (Lippai et al., 2008)

      Lethality acts in the third larval instar.

      (Deak et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      SNF4AγS005042 is partially rescued by Scer\GAL4hs.PU/SNF4AγUAS.RG

      (Lippai et al., 2008)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Precise excision of the P{lacW} insertion reverts the mutant phenotype.

      (Lippai et al., 2008)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      0050/42
      (Deak et al., 1997)
      SNF4AγS005042
      l(3)S005042S005042
      Name Synonyms
      Secondary FlyBase IDs
        References (3)