FlyBase Allele Report: Dmel\dome[G0264]

General Information

Symbol

Dmel\dome^G0264

Species

D. melanogaster

Name

FlyBase ID

FBal0100327

Feature type

allele

Associated gene

Dmel\dome

Associated Insertion(s)

P{lacW}dome^G0264

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

loss of function allele

Mutagen

P-element activity

Nature of the Allele

Allele class

loss of function allele

(Castelli-Gair Hombria, 2001.9.19)

Mutagen

P-element activity

(Schäfer et al., 1999.8.12)

Progenitor genotype

Associated Insertion(s)

P{lacW}dome^G0264

Cytology

Description

P{lacW} insertion in the 5' untranslated region.

(Chen et al., 2002)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:19,682,943..19,683,291 [-]

(Chen et al., 2002, Peter et al., 2002, Castelli-Gair Hombria, 2001.9.19, Schäfer et al., 1999.8.12)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

AJ427010

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Castelli-Gair Hombria, 2001.9.19, Schäfer et al., 1999.8.12)

lethal - all die before end of P-stage

(Peter et al., 2002)

some die during pharate adult stage

(Peter et al., 2002)

Phenotype Manifest In

embryonic/larval posterior spiracle

(Chen et al., 2002)

embryonic/larval spiracle

(Castelli-Gair Hombria, 2001.9.19)

Detailed Description

Statement

Reference

Homozygous embryos have a mild posterior spiracle defect.

(Chen et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

dome[+]/dome^G0264 is a suppressor of visible phenotype of Scer\GAL4^GMR.PF, upd1^UAS.cCa

(Chen et al., 2002)

Phenotype Manifest In

Suppressor of

Statement

Reference

dome[+]/dome^G0264 is a suppressor of eye phenotype of Scer\GAL4^GMR.PF, upd1^UAS.cCa

(Chen et al., 2002)

dome[+]/dome^G0264 is a suppressor of ommatidium | increased number phenotype of Scer\GAL4^GMR.PF, upd1^UAS.cCa

(Chen et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

111866

w^67c23 P{lacW}dome^G0264 P{neoFRT}19A/FM7c; P{ey-FLP.N}5

Notes on Origin

Discoverer

Comments

P{lacW} not verified as causing the lethality.

(Schäfer et al., 1999.8.12)

External Crossreferences and Linkouts ( 1 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AJ427010

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

dome^G0264

(Dong et al., 2025)

l(1)G0264

(Chen et al., 2002, Peter et al., 2002)

l(1)G0264^G0264

(Schäfer et al., 1999.8.12)

mom²

(Chen et al., 2002)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

Open Close