FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Hsap\GLI1αTub84B.Tag:MYC,Tag:HA
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General Information
Symbol
Hsap\GLI1αTub84B.Tag:MYC,Tag:HA
Species
H. sapiens
Name
FlyBase ID
FBal0102980
Feature type
allele
Associated gene
Hsap\GLI1
Associated Insertion(s)
Carried in Construct
P{αTub84B-Hsap\GLI}
Key Links
Transgenic product class
cDNA
(von Mering and Basler, 1999)
wild_type
(von Mering and Basler, 1999)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(von Mering and Basler, 1999)
wild_type
(von Mering and Basler, 1999)
Mutagen
in vitro construct
(von Mering and Basler, 1999)
Progenitor genotype
Carried in construct
P{αTub84B-Hsap\GLI}
Cytology
Description

A full length Hsap\GLI1 cDNA is fused to a Tag:MYC epitope at the extreme amino terminus, and to a triple Tag:HA epitope at the extreme carboxyl terminus all under the control of αTub84B promoter sequences.

(von Mering and Basler, 1999)
Allele components
Component
Use(s)
Regulatory region(s)
αTub84B
Encoded product / tool
Hsap\GLI1
Tagged with
Tag:HA
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Hsap\GLIαTub84B.T:Hsap\MYC,T:Ivir\HA1 causes a wing phenotype where the cubital vein L4 is interrupted.

      (von Mering and Basler, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Hsap\GLIαTub84B.T:Hsap\MYC,T:Ivir\HA1 rescues ci94 mutants to late larval stages. The wing discs of these animals are grossly enlarged. When Hsap\GLI3αTub84B.T:Hsap\MYC,T:Ivir\HA1 is also added, animals die as pupae or late larvae, and have wing discs of normal shape and size.

      (von Mering and Basler, 1999)

      Rescues ci94/Dp(1;4)1021 mutants to late larval lethality. The wing discs of these animals are grossly enlarged. When Hsap\GLI3αTub84B.T:Hsap\MYC,T:Ivir\HA1 is also added, animals die as pupae or late larvae, and have wing discs of normal shape and size.

      (von Mering and Basler, 1999)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Hsap\GLI1αTub84B.T:Hsap\MYC,T:Ivir\HA1
      Hsap\GLI1αTub84B.Tag:MYC,Tag:HA
      Hsap\GLIαTub84B.T:Hsap\MYC,T:Ivir\HA1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)