FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\αTub67CP40Δ
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General Information
Symbol
Dmel\αTub67CP40Δ
Species
D. melanogaster
Name
FlyBase ID
FBal0104379
Feature type
allele
Associated gene
Dmel\αTub67C
Associated Insertion(s)
P{?lacW}αTub67CP40Δ
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Matthies et al., 1999)
Progenitor genotype
αTub67CP40
(Matthies et al., 1999)
Associated Insertion(s)
P{?lacW}αTub67CP40Δ
Cytology
Description

A substantial internal portion of the P{lacW} element has been removed.

(Matthies et al., 1999)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygous females show high levels of achiasmate X chromosome nondisjunction, but the mutation has no or little effect on the segregation of chiasmate X chromosomes. Heterozygous females also show elevated levels of 4th chromosome nondisjunction (most of these 4th chromosome nondisjunction events are a secondary consequence of failures of X chromosome missegregation).

      (Matthies et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      αTub67CP40Δ has abnormal meiotic cell cycle | dominant phenotype, suppressible by nod3

      (Matthies et al., 1999)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The meiotic defects of heterozygotes are strongly suppressed if they are also heterozygous for nod3.

      (Matthies et al., 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      αTub67CP40Δ
      αtub67CP40Δ
      (Matthies et al., 1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)