FlyBase Allele Report: Dmel\tsg[UAS.cYa]

General Information

Symbol

Dmel\tsg^UAS.cYa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Yu

FlyBase ID

FBal0104926

Feature type

allele

Associated gene

Dmel\tsg

Associated Insertion(s)

Carried in Construct

P{UAS-tsg.Y}

Also Known As

UAS-tsg

Key Links

Transgenic product class

wild_type

(Yu et al., 2000)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Yu et al., 2000)

Mutagen

in vitro construct

(Yu et al., 2000)

Progenitor genotype

Carried in construct

P{UAS-tsg.Y}

Cytology

Description

UAS regulatory sequences drive tsg expression.

(Yu et al., 2000)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

tsg

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^A9

(Ross et al., 2001)

visible, with Scer\GAL4^Bx-MS1096

(Yu et al., 2004)

visible, with Scer\GAL4^unspecified

(Yu et al., 2000)

Phenotype Manifest In

wing, with Scer\GAL4^A9

(Ross et al., 2001)

wing vein, with Scer\GAL4^A9

(Ross et al., 2001)

wing vein, with Scer\GAL4^unspecified

(Yu et al., 2000)

wing vein | ectopic, with Scer\GAL4^Bx-MS1096

(Yu et al., 2004)

Detailed Description

Statement

Reference

Expression of tsg^Scer\UAS.cYa under the control of Scer\GAL4^Bx-MS1096 results in a mild ectopic vein phenotype in the wing.

(Yu et al., 2004)

Expression of tsg^Scer\UAS.cYa under the control of Scer\GAL4^unspecified causes a weak thick vein phenotype.

(Yu et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^Bx-MS1096, tsg^UAS.cYa has visible phenotype, non-enhanceable by sog^{ΔCR1-stem.UAS}/Scer\GAL4^Bx-MS1096

(Yu et al., 2004)

Suppressed by

Statement

Reference

Scer\GAL4^A9, sog^UAS.cYa, tsg^UAS.cYa has visible phenotype, suppressible by Scer\GAL4^A9/tok^{UAS.cSa.Tag:HA}

(Peluso et al., 2011)

Scer\GAL4^A9, dpp^UAS.cUa, tsg^UAS.cYa has visible phenotype, suppressible by Scer\GAL4^A9/sog^UAS.cYa

(Ross et al., 2001)

NOT suppressed by

Statement

Reference

Scer\GAL4^Bx-MS1096, tsg^UAS.cYa has visible phenotype, non-suppressible by sog^{ΔCR1-stem.UAS}/Scer\GAL4^Bx-MS1096

(Yu et al., 2004)

Enhancer of

Statement

Reference

Scer\GAL4^A9/tsg^UAS.cYa is an enhancer of visible phenotype of Scer\GAL4^A9, sog^UAS.cYa

(Peluso et al., 2011)

Suppressor of

Statement

Reference

Scer\GAL4^A9, sog^UAS.cYa, tsg^UAS.cYa is a suppressor | partially of visible phenotype of Scer\GAL4^A9, dpp^UAS.cUa

(Ross et al., 2001)

Scer\GAL4^A9/tsg^UAS.cYa is a suppressor of visible phenotype of Scer\GAL4^A9, dpp^UAS.cUa, sog^UAS.cYa

(Ross et al., 2001)

NOT Suppressor of

Statement

Reference

Scer\GAL4^ptc-559.1/tsg^UAS.cYa is a non-suppressor of visible phenotype of cv¹

(Vilmos et al., 2005)

Scer\GAL4^A9/tsg^UAS.cYa is a non-suppressor of visible phenotype of Scer\GAL4^A9, dpp^UAS.cUa

(Ross et al., 2001)

Other

Statement

Reference

Scer\GAL4^A9, sog^u.UAS, tok^{UAS.cSa.Tag:HA}, tsg^UAS.cYa has visible phenotype

(Peluso et al., 2011)

Scer\GAL4^A9, sog^UAS.cYa, tsg^UAS.cYa has visible phenotype

(Ross et al., 2001)

Scer\GAL4^A9, dpp^UAS.cUa, tsg^UAS.cYa has visible phenotype

(Ross et al., 2001)

Scer\GAL4^unspecified, sog^UAS.cYa, tsg^UAS.cYa has visible phenotype

(Yu et al., 2000)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^Bx-MS1096, tsg^UAS.cYa has wing vein | ectopic phenotype, non-enhanceable by sog^{ΔCR1-stem.UAS}/Scer\GAL4^Bx-MS1096

(Yu et al., 2004)

Suppressed by

Statement

Reference

Scer\GAL4^A9, sog^UAS.cYa, tsg^UAS.cYa has wing blade phenotype, suppressible by Scer\GAL4^A9/tok^{UAS.cSa.Tag:HA}

(Peluso et al., 2011)

Scer\GAL4^A9, sog^UAS.cYa, tsg^UAS.cYa has wing vein phenotype, suppressible by Scer\GAL4^A9/tok^{UAS.cSa.Tag:HA}

(Peluso et al., 2011, Serpe et al., 2005)

Scer\GAL4^A9, sog^UAS.cYa, tsg^UAS.cYa has wing phenotype, suppressible by Scer\GAL4^A9/tok^{UAS.cSa.Tag:HA}

(Serpe et al., 2005)

Scer\GAL4^A9, sog^UAS.cYa, tsg^UAS.cYa has wing phenotype, suppressible by Scer\GAL4^A9/tld^A.UAS.Tag:HA

(Serpe et al., 2005)

Scer\GAL4^A9, sog^UAS.cYa, tsg^UAS.cYa has wing vein phenotype, suppressible by Scer\GAL4^A9/tld^A.UAS.Tag:HA

(Serpe et al., 2005)

Scer\GAL4^A9, dpp^UAS.cUa, tsg^UAS.cYa has wing vein phenotype, suppressible by Scer\GAL4^A9/sog^UAS.cYa

(Ross et al., 2001)

Scer\GAL4^A9, dpp^UAS.cUa, tsg^UAS.cYa has wing phenotype, suppressible by Scer\GAL4^A9/sog^UAS.cYa

(Ross et al., 2001)

NOT suppressed by

Statement

Reference

Scer\GAL4^Bx-MS1096, tsg^UAS.cYa has wing vein | ectopic phenotype, non-suppressible by sog^{ΔCR1-stem.UAS}/Scer\GAL4^Bx-MS1096

(Yu et al., 2004)

Enhancer of

Statement

Reference

Scer\GAL4^A9/tsg^UAS.cYa is an enhancer of wing vein phenotype of Scer\GAL4^A9, sog^UAS.cYa

(Peluso et al., 2011)

Suppressor of

Statement

Reference

Scer\GAL4^A9/tsg^UAS.cYa is a suppressor of wing phenotype of Scer\GAL4^A9, gbb^UAS.cKa

(Vilmos et al., 2005)

Scer\GAL4^A9, sog^UAS.cYa, tsg^UAS.cYa is a suppressor of wing phenotype of Scer\GAL4^A9, gbb^UAS.cKa

(Vilmos et al., 2005)

Scer\GAL4^A9, sog^UAS.cYa, tsg^UAS.cYa is a suppressor | partially of wing vein phenotype of Scer\GAL4^A9, dpp^UAS.cUa

(Ross et al., 2001)

Scer\GAL4^A9, sog^UAS.cYa, tsg^UAS.cYa is a suppressor | partially of wing phenotype of Scer\GAL4^A9, dpp^UAS.cUa

(Ross et al., 2001)

Scer\GAL4^A9/tsg^UAS.cYa is a suppressor of wing vein phenotype of Scer\GAL4^A9, dpp^UAS.cUa, sog^UAS.cYa

(Ross et al., 2001)

Scer\GAL4^A9/tsg^UAS.cYa is a suppressor of wing phenotype of Scer\GAL4^A9, dpp^UAS.cUa, sog^UAS.cYa

(Ross et al., 2001)

NOT Suppressor of

Statement

Reference

Scer\GAL4^ptc-559.1/tsg^UAS.cYa is a non-suppressor of anterior crossvein phenotype of cv¹

(Vilmos et al., 2005)

Scer\GAL4^ptc-559.1/tsg^UAS.cYa is a non-suppressor of posterior crossvein phenotype of cv¹

(Vilmos et al., 2005)

Scer\GAL4^A9/tsg^UAS.cYa is a non-suppressor of wing vein phenotype of Scer\GAL4^A9, dpp^UAS.cUa

(Ross et al., 2001)

Scer\GAL4^A9/tsg^UAS.cYa is a non-suppressor of wing phenotype of Scer\GAL4^A9, dpp^UAS.cUa

(Ross et al., 2001)

Other

Statement

Reference

Scer\GAL4^A9, sog^UAS.cYa, tsg^UAS.cYa has wing blade phenotype

(Peluso et al., 2011)

Scer\GAL4^A9, sog^u.UAS, tok^{UAS.cSa.Tag:HA}, tsg^UAS.cYa has wing vein phenotype

(Peluso et al., 2011)

Scer\GAL4^A9, sog^u.UAS, tok^{UAS.cSa.Tag:HA}, tsg^UAS.cYa has wing blade phenotype

(Peluso et al., 2011)

Scer\GAL4^A9, sog^UAS.cYa, tsg^UAS.cYa has wing vein phenotype

(Serpe et al., 2005, Ross et al., 2001)

Scer\GAL4^A9, sog^UAS.cYa, tsg^UAS.cYa has wing phenotype

(Serpe et al., 2005)

Scer\GAL4^Bx-MS1096, Xlae\chrd.S^UAS.cYa, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^Bx-MS1096, sog^A2.UAS, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^Bx-MS1096, sog^{UAS.Tag:SS(ea)}, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^Bx-MS1096, sog^UAS.cYa, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^Bx-MS1096, sog^{supersog1.UAS}, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^Bx-MS1096, sog^{supersog2.UAS}, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^Bx-MS1096, sog^{supersog4.UAS}, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^Bx-MS1096, sog^A3.UAS, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^Bx-MS1096, sog^ΔCR1.UAS, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^Bx-MS1096, sog^A4.UAS, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^Bx-MS1096, sog^ΔCR2.UAS, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^Bx-MS1096, sog^ΔCR3.UAS, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^Bx-MS1096, sog^ΔCR4.UAS, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^Bx-MS1096, sog^A1.UAS, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^Bx-MS1096, sog^{A1.supersog1.UAS}, tsg^UAS.cYa has wing phenotype

(Yu et al., 2004)

Scer\GAL4^A9, dpp^UAS.cUa, tsg^UAS.cYa has wing phenotype

(Ross et al., 2001)

Scer\GAL4^A9, dpp^UAS.cUa, tsg^UAS.cYa has wing vein phenotype

(Ross et al., 2001)

Scer\GAL4^unspecified, sog^UAS.cYa, tsg^UAS.cYa has wing phenotype

(Yu et al., 2000)

Scer\GAL4^unspecified, sog^UAS.cYa, tsg^UAS.cYa has wing vein phenotype

(Yu et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

Overexpression of sog^Scer\UAS.cYa together with tsg^Scer\UAS.cYa under the control of Scer\GAL4^A9 results in smaller wings with altered patterns of venation.

Co-overexpression of tok^{Scer\UAS.cSa.T:Ivir\HA1} with sog^Scer\UAS.cYa and tsg^Scer\UAS.cYa under the control of Scer\GAL4^A9 is able to reverse the sog^Scer\UAS.cYa-tsg^Scer\UAS.cYa small-wing phenotype and restore normal patterning.

Co-overexpression of tok^{Scer\UAS.cSa.T:Ivir\HA1} with sog^u.Scer\UAS and tsg^Scer\UAS.cYa under the control of Scer\GAL4^A9 results in a small-wing phenotype and abnormal wing vein patterning.

(Peluso et al., 2011)

Coexpression of sog^Scer\UAS.cYa and tsg^Scer\UAS.cYa in the wing disc, under the control of Scer\GAL4^A9, produces a small wing with altered patterns of venation. Coexpression of either tld^{A.Scer\UAS.T:Ivir\HA1} or tok^Scer\UAS.cSa with these two transgenes is able to reverse the small wing phenotype and restore normal patterning.

(Serpe et al., 2005)

When tsg^Scer\UAS.cYa and cv-2^Scer\UAS.cVa are co-expressed under the regulation of Scer\GAL4^A9, there is no evidence of strong BMP inhibition. When tsg^Scer\UAS.cYa and sog^Scer\UAS.cYa are co-expressed under the regulation of Scer\GAL4^A9, there is strong BMP inhibition. Co-expression of tsg^Scer\UAS.cYa and dpp^Scer\UAS.cHa, under the regulation of Scer\GAL4^A9 has no detectable effect on the over expression phenotype of dpp^Scer\UAS.cHa, indicating that tsg alone does not interact with dpp. Co-expression of tsg^Scer\UAS.cYa and gbb^Scer\UAS.cKa, under the regulation of Scer\GAL4^A9 suppresses the excess gbb phenotype. Co-expression of tsg^Scer\UAS.cYa and sog^Scer\UAS.cYa, along with gbb^Scer\UAS.cKa, under the regulation of Scer\GAL4^A9 partially suppresses the excess gbb^Scer\UAS.cKa wing disruption phenotype.

(Vilmos et al., 2005)

Expression of sog^Scer\UAS.cYa and tsg^Scer\UAS.cYa, but not either alone, driven by Scer\GAL4^A9 rescues the wing shape and wing vein phenotype of dpp^Scer\UAS.cHa driven by Scer\GAL4^A9. When expression of sog^Scer\UAS.cYa is driven by Scer\GAL4^A9 in combination with tsg^Scer\UAS.cYa, Hsap\TSG^Scer\UAS.cRa or Mmus\Tsg^Scer\UAS.cRa, gaps in the distal section of the wing veins occur.

(Ross et al., 2001)

Co-expression of tsg^Scer\UAS.cYa and sog^Scer\UAS.cYa under the control of Scer\GAL4^unspecified causes a strong synergistic wing phenotype.

(Yu et al., 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

606404

y¹ w^*; P{UAS-tsg.Y}2/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

tsg^Scer\UAS.cYa

tsg^UAS.cYa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Yu

(Yu et al., 2000)

Secondary FlyBase IDs

References (6)

Report Sections

Open Close