FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\nejEP1410
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General Information
Symbol
Dmel\nejEP1410
Species
D. melanogaster
Name
FlyBase ID
FBal0104982
Feature type
allele
Associated gene
Dmel\nej
Associated Insertion(s)
P{EP}nejEP1410
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-, Marek et al., 2000)
Progenitor genotype
Associated Insertion(s)
P{EP}nejEP1410
Cytology
Description

P{EP} element insertion approximately 3kb upstream of the nej open reading frame, in the 5' UTR. The orientation of the P{EP} element is such that the 5' end of the P{EP} element is proximal to the nej open reading frame.

(Marek et al., 2000)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  neurodegenerative disease
      modeled by Hsap\ATXN3tr.Q78.UAS.Tag:HA
      (Huen and Chan, 2005)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of nejEP1410 under the control of Scer\GAL4GMR.PU does not cause degeneration or pigment loss in the adult eye.

      (Huen and Chan, 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      The progressive degeneration and pigmentation loss eye phenotype characteristic for flies expressing Hsap\ATXN3tr.Q78.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4GMR.PU is partially suppressed by co-expression of nejEP1410.

      (Huen and Chan, 2005)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      nejEP1410
      (Huen and Chan, 2005)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)