FlyBase Allele Report: Dmel\trio[GEF2.UAS.Tag:MYC]

General Information

Symbol

Dmel\trio^{GEF2.UAS.Tag:MYC}

Species

D. melanogaster

Name

FlyBase ID

FBal0117291

Feature type

allele

Associated gene

Dmel\trio

Associated Insertion(s)

Carried in Construct

P{UAS-trio.GEF2}

Key Links

Transgenic product class

inframe_deletion

(Newsome et al., 2000)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

inframe_deletion

(Newsome et al., 2000)

Mutagen

in vitro construct

(Newsome et al., 2000)

Progenitor genotype

Carried in construct

P{UAS-trio.GEF2}

Cytology

Description

UAS regulatory sequences drive expression of the trio GEF2 domain, tagged at the 3' end with 8 copies of the Tag:MYC tag.

(Newsome et al., 2000)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

trio

Tagged with

Tag:MYC

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | larval stage, with Scer\GAL4^ppk.PG

(Lancaster et al., 2024)

viable, with Scer\GAL4^ey-OK107

(Lancaster et al., 2024)

Phenotype Manifest In

dendritic branch | larval stage, with Scer\GAL4^ppk.PG

(Lancaster et al., 2024)

larval dorsal multidendritic neuron ddaC, with Scer\GAL4^ppk.PG

(Lancaster et al., 2024)

Detailed Description

Statement

Reference

Expression of trio^{GEF2.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^OK107 does not result in any gross defects in the mushroom body.

(Ng and Luo, 2004)

Expression of trio^{GEF2.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^GMR.PF does not cause defects in photoreceptor axon projection.

(Newsome et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Scer\GAL4^ey-OK107/trio^{GEF2.UAS.Tag:MYC} is a non-enhancer of short lived phenotype of Nab2^ex3

(Lancaster et al., 2024)

Suppressor of

Statement

Reference

Scer\GAL4^ppk.PG/trio^{GEF2.UAS.Tag:MYC} is a suppressor of abnormal neuroanatomy | larval stage phenotype of Nab2^ex3

(Lancaster et al., 2024)

Scer\GAL4^ey-OK107/trio^{GEF2.UAS.Tag:MYC} is a suppressor | partially of increased mortality during development phenotype of Nab2^ex3

(Lancaster et al., 2024)

Scer\GAL4^ey-OK107/trio^{GEF2.UAS.Tag:MYC} is a suppressor | partially of decreased rate of adult locomotory behavior phenotype of Nab2^ex3

(Lancaster et al., 2024)

Scer\GAL4^c305a/trio^{GEF2.UAS.Tag:MYC} is a suppressor | partially of abnormal neuroanatomy | adult stage phenotype of Nab2^ex3

(Lancaster et al., 2024)

NOT Suppressor of

Statement

Reference

Scer\GAL4^ey-OK107/trio^{GEF2.UAS.Tag:MYC} is a non-suppressor of short lived phenotype of Nab2^ex3

(Lancaster et al., 2024)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^ppk.PG/trio^{GEF2.UAS.Tag:MYC} is a suppressor of dendritic branch | larval stage phenotype of Nab2^ex3

(Lancaster et al., 2024)

Scer\GAL4^ey-OK107/trio^{GEF2.UAS.Tag:MYC} is a suppressor of adult mushroom body alpha-lobe phenotype of Nab2^ex3

(Lancaster et al., 2024)

Scer\GAL4^c305a/trio^{GEF2.UAS.Tag:MYC} is a suppressor of adult mushroom body alpha'-lobe phenotype of Nab2^ex3

(Lancaster et al., 2024)

Scer\GAL4^c305a/trio^{GEF2.UAS.Tag:MYC} is a suppressor | partially of adult mushroom body beta'-lobe phenotype of Nab2^ex3

(Lancaster et al., 2024)

Scer\GAL4^ppk.PG/trio^{GEF2.UAS.Tag:MYC} is a suppressor of larval dorsal multidendritic neuron ddaC phenotype of Nab2^ex3

(Lancaster et al., 2024)

NOT Suppressor of

Statement

Reference

Scer\GAL4^ey-OK107/trio^{GEF2.UAS.Tag:MYC} is a non-suppressor of adult mushroom body beta-lobe phenotype of Nab2^ex3

(Lancaster et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

9134

y¹ w^*; P{UAS-trio.GEF2}3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

trio^{GEF2.Scer\UAS.T:Hsap\MYC}

trio^{GEF2.UAS.Tag:MYC}

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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