FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\jumuL70
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General Information
Symbol
Dmel\jumuL70
Species
D. melanogaster
Name
FlyBase ID
FBal0118186
Feature type
allele
Associated gene
Dmel\jumu
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Cheah et al., 2000)
Mutagen
P-element activity
(Cheah et al., 2000)
Progenitor genotype
jumu06439
(Cheah et al., 2000)
Cytology
Description

"Point" mutation.

(Cheah et al., 2000)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous and jumuL70/Df(3R)B22-5 embryos show duplication of the RP2 neuron (expressivity of the phenotype is 29% and 23% respectively). Homozygous embryos show greater than 95% penetrance of the RP2 neuron duplication phenotype. The extra RP2 neuron appears to be derived from the RP2sib cell. The GMC4-2a cell appears to retain a wild-type identity in homozygous embryos.

      (Cheah et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      jumuL70 is a suppressor of eye phenotype of Scer\GAL4hs.2sev, mblC.UAS

      (Vicente-Crespo et al., 2008)

      jumuL70 is a suppressor of wing vein L4 phenotype of Scer\GAL4e22c, mblC.UAS

      (Vicente-Crespo et al., 2008)

      jumuL70 is a suppressor of wing vein L5 phenotype of Scer\GAL4e22c, mblC.UAS

      (Vicente-Crespo et al., 2008)

      jumuL70 is a suppressor of wing cell phenotype of Scer\GAL4e22c, mblC.UAS

      (Vicente-Crespo et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      A jumuL70 mutant background suppresses the moderately rough eye phenotype observed upon expression of mblC.Scer\UAS under the control of Scer\GAL4hs.2sev.

      A jumuL70 mutant background reduces L4/L5 vein fusion events and also ameliorates several other aspects of the mblC.Scer\UAS (under the control of Scer\GAL4e22c) phenotype such as loss of laminar wing tissue or anterior intervein.

      (Vicente-Crespo et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      jumuL70
      (Vicente-Crespo et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)