FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\crcUAS.cHa
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General Information
Symbol
Dmel\crcUAS.cHa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Hewes
FlyBase ID
FBal0118282
Feature type
allele
Associated gene
Dmel\crc
Associated Insertion(s)
Carried in Construct
P{UAS-crc.H}
Also Known As
UAS-crc
Key Links
Transgenic product class
cDNA
(Hewes et al., 2000)
wild_type
(Hewes et al., 2000)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Hewes et al., 2000)
wild_type
(Hewes et al., 2000)
Mutagen
in vitro construct
(Hewes et al., 2000)
Progenitor genotype
Carried in construct
P{UAS-crc.H}
Cytology
Description

UASt regulatory sequences drive expression of the crc-c mRNA (which encodes the crc B protein isoform).

(Hewes et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
crc
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heat shock induced expression of crcScer\UAS.cHa under the control of Scer\GAL4hs.PH results in substantial lethality in an otherwise wild-type background.

      (Hewes et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4dimm-929/crcUAS.cHa rescues crc929

      (Hewes et al., 2000)
      Partially rescues

      crcUAS.cHa partially rescues crc1/Df(2L)Rev8

      (Hewes et al., 2000)
      Comments

      6 out of 7 crcScer\UAS.cHa lines rescue 8-21% of the lethality of crc1/Df(2L)Rev8 flies. This rescue is constitutive, occurring in the absence of a Scer\GAL4 driver, presumably reflecting basal expression of the P{UAS-crc.H} construct.

      (Hewes et al., 2000)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      crcScer\UAS.cHa
      crcUAS.cHa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Hewes
      (Hewes et al., 2000)
      Secondary FlyBase IDs
        References (2)