FlyBase Allele Report: Dmel\ebi[unspecified]

General Information

Symbol

Dmel\ebi^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0119258

Feature type

allele

Associated gene

Dmel\ebi

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal mitotic cell cycle | embryonic stage 13

(Boulton et al., 2000)

decreased cell number | embryonic stage

(Boulton et al., 2000)

increased occurrence of cell division | embryonic stage

(Boulton et al., 2000)

Phenotype Manifest In

antenna

(Marygold et al., 2011)

eye

(Marygold et al., 2011)

leg

(Marygold et al., 2011)

macrochaeta | ectopic

(Marygold et al., 2011)

neuron | embryonic stage

(Boulton et al., 2000)

presumptive embryonic/larval peripheral nervous system

(Boulton et al., 2000)

wing margin

(Marygold et al., 2011)

Detailed Description

Statement

Reference

Less penetrant and more variable morphological defects observed in ebi transheterozygotes include stunted and ectopic macrochaetae in the notum, notching of the wing margin, slight roughening of the eye, malformed legs, and abnormal growths in the antennal region.

(Marygold et al., 2011)

ebi^unspecified mutant embryos display ectopic S phases in the peripheral nervous system (PNS) and central nervous system at stage 13 of embryogenesis. Mutants also display defects in embryonic PNS development. The severity of this phenotype varies and in a majority of cases only a small number of the neurons are missing.

(Boulton et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

ebi^unspecified/ebi[+] is an enhancer of phenotype of Egfr^f2

(Dong et al., 1999)

ebi^unspecified/ebi[+] is an enhancer of phenotype of Egfr^t1

(Dong et al., 1999)

Suppressor of

Statement

Reference

ebi^unspecified/ebi[+] is a suppressor of eye disc & mitotic cell cycle phenotype of Hsap\CDKN1A^GMR.PH

(Boulton et al., 2000)

ebi^unspecified/ebi[+] is a suppressor of eye phenotype of Hsap\CDKN1A^GMR.PH

(Boulton et al., 2000)

ebi^unspecified/ebi[+] is a suppressor of interommatidial bristle phenotype of Hsap\CDKN1A^GMR.PH

(Boulton et al., 2000)

ebi^unspecified/ebi[+] is a suppressor of ommatidium phenotype of Hsap\CDKN1A^GMR.PH

(Boulton et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

ebi^unspecified

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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