FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Sin3AEP866
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General Information
Symbol
Dmel\Sin3AEP866
Species
D. melanogaster
Name
FlyBase ID
FBal0119387
Feature type
allele
Associated gene
Dmel\Sin3A
Associated Insertion(s)
P{EP}Sin3AEP866
Carried in Construct
Also Known As
EP866
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-, Fernandez-Funez et al., 2000)
Progenitor genotype
Associated Insertion(s)
P{EP}Sin3AEP866
Cytology
Description

The P{EP} insertion is 4601bp downstream of the putative ATG start codon in the opposite orientation to the transcription unit.

(Fernandez-Funez et al., 2000)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Sin3AEP866 under the control of Scer\GAL4GMR.PF does not result in a rough eye phenotype.

      (Shulman and Feany, 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Sin3AEP866 is an enhancer of visible phenotype of IswiK159R.UAS.Tag:HA, Scer\GAL4ey.PH

      (Burgio et al., 2008)
      NOT Enhancer of
      Statement
      Reference

      Sin3AEP866, Scer\GAL4GMR.PF is a non-enhancer of visible phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PF

      (Shulman and Feany, 2003)
      NOT Suppressor of
      Statement
      Reference

      Sin3AEP866, Scer\GAL4GMR.PF is a non-suppressor of visible phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PF

      (Shulman and Feany, 2003)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Sin3AEP866 is an enhancer of eye phenotype of IswiK159R.UAS.Tag:HA, Scer\GAL4ey.PH

      (Burgio et al., 2008)
      NOT Enhancer of
      Statement
      Reference

      Sin3AEP866, Scer\GAL4GMR.PF is a non-enhancer of eye phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PF

      (Shulman and Feany, 2003)
      NOT Suppressor of
      Statement
      Reference

      Sin3AEP866, Scer\GAL4GMR.PF is a non-suppressor of eye phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PF

      (Shulman and Feany, 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The severity of the mutant eye phenotype caused by expression of IswiK159R.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4ey.PH is enhanced by Sin3AEP866.

      (Burgio et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference

      The rough eye phenotype caused by expression of Hsap\MAPTV337M.Scer\UAS under the control of Scer\GAL4GMR.PF is not modified if the flies are also carrying Sin3AEP866.

      (Shulman and Feany, 2003)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      EP(2)0866
      (Shulman and Feany, 2003)
      Sin3AEP866
      Name Synonyms
      Secondary FlyBase IDs
        References (5)