FlyBase Allele Report: Dmel\zld[EP1344]

General Information

Symbol

Dmel\zld^EP1344

Species

D. melanogaster

Name

FlyBase ID

FBal0119650

Feature type

allele

Associated gene

Dmel\zld

Associated Insertion(s)

P{EP}zld^EP1344

Carried in Construct

Also Known As

EP(X)1344

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000)

Progenitor genotype

Associated Insertion(s)

P{EP}zld^EP1344

Cytology

Description

P{EP} insertion.

(Abdelilah-Seyfried et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:19,783,589..19,783,589 [-]

(Staudt et al., 2006, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal mitotic cell cycle | embryonic stage, with Scer\GAL4^{VP16.mat.αTub67C}

(Staudt et al., 2006)

abnormal neuroanatomy, with Scer\GAL4^ftz.ng

(Staudt et al., 2006)

visible, with Scer\GAL4^ftz.ng

(Staudt et al., 2006)

visible, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

Phenotype Manifest In

axon, with Scer\GAL4^ftz.ng

(Staudt et al., 2006)

dorsocentral bristle, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

larval neuron, with Scer\GAL4^ftz.ng

(Staudt et al., 2006)

scutellar bristle, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

tormogen cell, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

wing blade, with Scer\GAL4^ftz.ng

(Staudt et al., 2006)

Detailed Description

Statement

Reference

Expression of vfl^EP1344 under the control of Scer\GAL4^ftz.ng results in loss of neurons and axonal fractures in the embryo.

Expression of vfl^EP1344 under the control of Scer\GAL4^ap-md544 results in wing blisters.

Expression of vfl^EP1344 under the control of Scer\GAL4^{mat.αTub67C.T:Hsim\VP16} results in embryos with irregular early mitotic waves.

(Staudt et al., 2006)

Expression of EP1344^EP1344 under the control of Scer\GAL4^sca-537.4 results in the loss or ectopic position of several scutellar and dorsocentral macrochaetae. Socket morphology is abnormal.

(Abdelilah-Seyfried et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

EP(X)1344

(Abdelilah-Seyfried et al., 2000)

EP1344^EP1344

vfl^EP1344

zld^EP1344

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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