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General Information
Symbol
Dmel\neurGAL4-A101
Species
D. melanogaster
Name
FlyBase ID
FBal0120429
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
neur-Gal4, neuralized-GAL4, neu-gal4, neuralised-GAL4, neurGal4
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

The P{lArB} element in neurA101 has been replaced with the P{GawB} element from P{GawB}SG18.1 by P\T-mediated conversion.

The P{lArB} sequences of the neurA101 insertion have been replaced with P{GAL4} sequences.

The P{lArB} element of neurA101 has been replaced with a P{GAL4} element.

Insertion components
P{GawB}neurGAL4-A101
Product class / Tool use(s)
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

neurGAL4-A101 heterozygotes exhibit learning and 9-minute memory abilities that appear identical to wild-type controls. However, these animals display significantly reduced 260-minute memory. This memory deficit is detectable 24 hours later. These mutants do not exhibit deficiencies in the perception of conditioned stimuli (CS) and unconditioned stimuli (US) or detectable aberrations in the architecture of the brain and the mushroom bodies.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of neurScer\UAS.PA.T:SV5\V5 under the control of Scer\GAL4neur-GAL4-A101 strongly rescues the neurogenic phenotype of homozygous neurGAL4-A101 embryos.

Expression of neurG430E.Scer\UAS.PA.T:SV5\V5 under the control of Scer\GAL4neur-GAL4-A101 fails to rescue the neurogenic phenotype of homozygous neurGAL4-A101 embryos.

Expression of neurΔNH2.Scer\UAS.PA.T:SV5\V5 under the control of Scer\GAL4neur-GAL4-A101 may have some residual rescue activity of the neurogenic phenotype of homozygous neurGAL4-A101 embryos.

Expression of neurScer\UAS.PA.T:SV5\V5 under the control of Scer\GAL4neur-GAL4-A101 strongly rescues the neurogenic phenotype of homozygous neurGAL4-A101 embryos.

Expression of neur5Q.Scer\UAS.PA.T:SV5\V5 under the control of Scer\GAL4neur-GAL4-A101 fails to rescue the neurogenic phenotype of homozygous neurGAL4-A101 embryos.

Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
neurA101GAL4
neurGAL4-A101
neurGAL4
neur[GAL4-A101]
Name Synonyms
Secondary FlyBase IDs
  • FBal0102505
References (6)