Polar follicle cell specification occurs in clones induced in somatic stem cells and their descendents. Relatively large somatic clones that include the anterior region of the follicular epithelium of an egg chamber are associated with the production of egg chambers with abnormal numbers of germline cells.
Germ cells in embryos lacking maternal fu function (derived from females carrying fumH63 germline clones and fertilised with a wild-type sperm) migrate towards the somatic gonadal precursor cells but fail to properly associate with them and instead scatter through the posterior half of the embryo. These embryos do not hatch.
Mutant embryos derived from homozygous germline clones lack Bolwig's organs.
fumH63 mutant clones at the AP border of the wing invade posterior compartment territory and induce a central vein 3 decorated with sensillae at the position normally occupied by vein 4. Wing morphology is not affected in clones outside the region usually affected by hh signalling.
Homozygotes display a strong fu wing phenotype.
Pharates die with a strong fused wing phenotype.
Homozygous and hemizygous females and hemizygous males die in pupal stage; lethality suppressible by Su(fu). fumH63/fu41 and fumH63/Y have all segments entirely duplicated; lack mouth hooks and some have no head. fumH63/+ embryos from such clones exhibit very low paternal rescue; small correction of segmental phenotype, low hatch and preadult mortality (Busson et al. 1988). pupal lethal