FB2026_02 , released June 18, 2026
Allele: Dmel\gsb::prd+PRD
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General Information
Symbol
Dmel\gsb::prd+PRD
Species
D. melanogaster
Name
FlyBase ID
FBal0121745
Feature type
allele
Associated gene
gsb::prd
Associated Insertion(s)
Carried in Construct
P{prd-gsb.+PRD}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Xue et al., 2001)
Progenitor genotype
gsbprd.PX
(Xue et al., 2001)
Carried in construct
P{prd-gsb.+PRD}
Cytology
Description

Construct: The last 12 amino acids of gsb have been replaced with the 118 amino acid C-terminal end of prd, which includes the PRD (His-Pro) repeat.

(Xue et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
prd
Encoded product / tool
gsb::prd
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      gsb::prd+PRD is a non-suppressor of male sterile phenotype of Df(2L)Prl/prd4

      (Xue et al., 2001)
      Other
      Statement
      Reference

      Df(2L)Prl/prd4, gsb::prd+PRD has viable | adult stage phenotype

      (Xue et al., 2001)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      gsb::prd+PRD is a suppressor of embryonic/first instar larval cuticle phenotype of prd4

      (Xue et al., 2001)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      One copy of gsb::prd+PRD fully rescues the cuticle phenotype of prd4 homozygous embryos. Two copies of gsb::prd+PRD fully rescue prd4/Df(2L)Prl animals to adulthood, while one copy partially rescues prd4/Df(2L)Prl viability. Two copies of gsb::prd+PRD fail to rescue the fertility of prd4/Df(2L)Prl males.

      (Xue et al., 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      gsb::prd+PRD
      Name Synonyms
      Secondary FlyBase IDs
        References (1)