FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\gsb::MmusPax3GsbN+Pax3C.prd
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General Information
Symbol
Dmel\gsb::Mmus\Pax3GsbN+Pax3C.prd
Species
D. melanogaster
Name
FlyBase ID
FBal0121748
Feature type
allele
Associated gene
gsb::Mmus\Pax3
Associated Insertion(s)
Carried in Construct
P{prd-GsbN+Pax3C}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Xue et al., 2001)
Progenitor genotype
gsbprd.PX
(Xue et al., 2001)
Carried in construct
P{prd-GsbN+Pax3C}
Cytology
Description

Construct: The C-terminal part of gsb has been replaced with the C-terminal part of Mmus\Pax3.

(Xue et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
prd
Encoded product / tool
gsb::Mmus\Pax3
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      gsbprd.PX/gsb::Mmus\Pax3GsbN+Pax3C.prd is a non-suppressor of male sterile phenotype of Df(2L)Prl/prd4

      (Xue et al., 2001)
      Other
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      One copy of gsb::Mmus\Pax3GsbN+Pax3C.prd partially rescues the cuticle phenotype of prd4 homozygous embryos, while two copies fully rescue the phenotype. Two copies of gsb::Mmus\Pax3GsbN+Pax3C.prd fail to rescue prd4/Df(2L)Prl animals to adulthood. Two copies of gsb::Mmus\Pax3GsbN+Pax3C.prd fail to rescue the fertility of prd4/Df(2L)Prl males (in a background where prd4/Df(2L)Prl viability has been rescued by one copy of gsbprd.PX).

      (Xue et al., 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      gsb::Mmus\Pax3GsbN+Pax3C.prd
      Name Synonyms
      Secondary FlyBase IDs
        References (1)