FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Relunspecified
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General Information
Symbol
Dmel\Relunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0122000
Feature type
allele
Associated gene
Dmel\Rel
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mutant flies show reduced survival compared to wild-type controls after challenge with a needle contaminated with A. tumefaciens.

        (Leclerc et al., 2006)

        Bacteria injected into mutant larvae or adults show increased survival compared to those injected into wild type. Phenotype is similar to that shown by ird5 mutants.

        (Lu et al., 2001)

        Mutant larvae show normal melanisation at a wound site in response to infection and do not have melanotic tumours.

        (Wu et al., 2001)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Other
        Statement
        Reference

        Difunspecified, Relunspecified has abnormal immune response | temperature conditional phenotype

        (Pilátová and Dionne, 2012)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Relunspecified Difunspecified double mutants show no increase in susceptibility compared to wild type when infected with exponential-phase B. thaliandensis at 25[o]C. The double mutant flies are consistently slightly longer lived than controls. When Relunspecified Difunspecified double mutant flies are infected with B. thaliandensis at 18[o]C they die much faster than wild type flies. As in wild type flies, infecting the Relunspecified Difunspecified double mutant flies with mutant forms of B. thaliandensis that affect either the Type II (T3SS) or Type VI (T6SS) secretion systems has no effect on survival compared with wild type B.thaliandensis.

        (Pilátová and Dionne, 2012)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Fails to complement

        RelE20

        (Wu et al., 2001)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Relunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (12)