FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\bratUAS.cSa
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General Information
Symbol
Dmel\bratUAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Sonada
FlyBase ID
FBal0123027
Feature type
allele
Associated gene
Dmel\brat
Associated Insertion(s)
Carried in Construct
P{UAS-brat.S}
Also Known As
UAS-brat
Key Links
Transgenic product class
wild_type
(Sonoda and Wharton, 2001)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Sonoda and Wharton, 2001)
Mutagen
in vitro construct
(Sonoda and Wharton, 2001)
Progenitor genotype
Carried in construct
P{UAS-brat.S}
Cytology
Description

UAS sequences drive expression of full length brat.

(Sonoda and Wharton, 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
brat
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      bratScer\UAS.cSa when driven by Scer\GAL4en-e16E produces adult wings that ard 24% smaller than wild-type. They are also usually deformed. The reduction in wing size appears to be due to a reduction in the number of cells contributing to the wing, rather than a reduction in the size of cells. This phenotype is also cell non-autonomous, as the anterior compartment of the wing is also affected.

      (Sonoda and Wharton, 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      bratUAS.cSa is partially rescued by Scer\GAL4αTub84B.PL, bratUAS.cSa

      (Bello et al., 2006)
      Rescues

      bratUAS.cSa/Scer\GAL4VP16.nanos.UTR rescues bratfs1

      (Sonoda and Wharton, 2001)
      Partially rescues

      Scer\GAL4αTub84B.PL, bratUAS.cSa partially rescues bratUAS.cSa

      (Bello et al., 2006)
      Comments

      Expression of bratScer\UAS.cSa under the control of Scer\GAL4αTub84B.PL in brat11 mutant clones partially rescues the overproliferation phenotype in the central larval brain.

      (Bello et al., 2006)

      bratScer\UAS.cSa when driven by Scer\GAL4nos.UTR.T:Hsim\VP16 rescues the abdominal phenotype of bratfs1/Df embryos.

      (Sonoda and Wharton, 2001)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      bratScer\UAS.cSa
      bratUAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Sonada
      Secondary FlyBase IDs
        References (5)