FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\smoEP1220
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General Information
Symbol
Dmel\smoEP1220
Species
D. melanogaster
Name
FlyBase ID
FBal0123692
Feature type
allele
Associated gene
Dmel\smo
Associated Insertion(s)
P{EP}smoEP1220
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Pena-Rangel et al., 2002, Gene Disruption Project members, 2001-, Glazer and Shilo, 2001)
Progenitor genotype
Associated Insertion(s)
P{EP}smoEP1220
Cytology
Description

P{EP} insertion 389bp downstream of the transcription start site, in codon 28. The orientation of the element is opposite to the direction of smo transcription.

(Glazer and Shilo, 2001)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of smoEP1220 under the control of Scer\GAL4ey.PH has no effect on the eye.

      (Singh et al., 2005)

      Embryos expressing smoEP1220 under the control of Scer\GAL4btl.PS show defects only in late stages of tracheal development; a lack of terminal branching in the dorsal tracheal branch is seen.

      (Glazer and Shilo, 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      smoEP1220/Scer\GAL4pnr-MD237 is an enhancer of visible phenotype of pnrMD237

      (Pena-Rangel et al., 2002)
      Suppressor of
      Statement
      Reference

      smoEP1220/Scer\GAL4ey.PH is a suppressor of visible | dominant phenotype of L2

      (Singh et al., 2005)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      smoEP1220/Scer\GAL4ey.PH is a suppressor of eye | ventral phenotype of L2

      (Singh et al., 2005)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      pnrMD237/+ adults expressing P{EP}smoEP1220 under the control of Scer\GAL4pnr-MD237 have a deformed scutellum.

      (Pena-Rangel et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: a P{EP} insertion line that modifies the pnrMD237/+ phenotype when expressed using Scer\GAL4pnr-MD237.

      (Pena-Rangel et al., 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      EP(2)1220
      (Glazer and Shilo, 2001)
      smoEP1220
      Name Synonyms
      Secondary FlyBase IDs
        References (4)