FlyBase Allele Report: Dmel\sbb[270]

General Information

Symbol

Dmel\sbb²⁷⁰

Species

D. melanogaster

Name

FlyBase ID

FBal0123713

Feature type

allele

Associated gene

Dmel\sbb

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(LaJeunesse et al., 2001)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of pupal stage | recessive

(LaJeunesse et al., 2001)

some die during pupal stage | recessive

(LaJeunesse et al., 2001)

Phenotype Manifest In

wing vein | ectopic (with sbb³²⁴)

(LaJeunesse et al., 2001)

Detailed Description

Statement

Reference

sbb²⁷⁰/sbb³²⁴ rare escapers have ectopic wing vein material.

(LaJeunesse et al., 2001)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

sbb²⁷⁰ is an enhancer of partially lethal | recessive | male phenotype of Mer³

(LaJeunesse et al., 2001)

sbb²⁷⁰ is an enhancer of visible phenotype of Mer^{ΔBB.UAS.Tag:MYC}, Scer\GAL4^en-e16E

(LaJeunesse et al., 2001)

Other

Statement

Reference

bs²⁴², sbb²⁷⁰ has visible | dominant phenotype

(LaJeunesse et al., 2001)

bs[+]/bs²⁴², sbb²⁷⁰ has visible | dominant phenotype

(LaJeunesse et al., 2001)

Phenotype Manifest In

Enhanced by

Statement

Reference

sbb²⁷⁰ has wing blade posterior compartment phenotype, enhanceable by Scer\GAL4^en-e16E/Mer^{ΔBB.UAS.Tag:MYC}

(LaJeunesse et al., 2001)

Enhancer of

Statement

Reference

sbb²⁷⁰ is an enhancer of posterior crossvein phenotype of Mer^{ΔBB.UAS.Tag:MYC}, Scer\GAL4^en-e16E

(LaJeunesse et al., 2001)

sbb²⁷⁰ is an enhancer of wing vein L5 phenotype of Mer^{ΔBB.UAS.Tag:MYC}, Scer\GAL4^en-e16E

(LaJeunesse et al., 2001)

sbb²⁷⁰ is an enhancer of wing vein | ectopic phenotype of Mer^{ΔBB.UAS.Tag:MYC}, Scer\GAL4^en-e16E

(LaJeunesse et al., 2001)

Other

Statement

Reference

bs²⁴², sbb²⁷⁰ has wing phenotype

(LaJeunesse et al., 2001)

bs²⁴², sbb²⁷⁰ has wing vein | ectopic phenotype

(LaJeunesse et al., 2001)

bs[+]/bs²⁴², sbb²⁷⁰ has wing phenotype

(LaJeunesse et al., 2001)

bs[+]/bs²⁴², sbb²⁷⁰ has wing vein | ectopic phenotype

(LaJeunesse et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

sbb²⁷⁰ bs²⁴² double heterozygotes show wing blistering and ectopic vein material in many cases.

(LaJeunesse et al., 2001)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Allele strength (based on hemizygous lethal period): sbb²⁷⁰, sbb²⁵⁶, sbb¹⁵¹ > sbb³²⁴, sbb²⁵⁹.

(LaJeunesse et al., 2001)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

IIa-bks²⁷⁰

(LaJeunesse et al., 2001)

sbb²⁷⁰

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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