FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sbb324
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General Information
Symbol
Dmel\sbb324
Species
D. melanogaster
Name
FlyBase ID
FBal0123712
Feature type
allele
Associated gene
Dmel\sbb
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(LaJeunesse et al., 2001)
Progenitor genotype
Cytology
Description

Amino acid replacement: Q1608term.

(LaJeunesse et al., 2001)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:18,282,441..18,282,441 [-]
Nucleotide change:

C18282441T

Amino acid change:

Q1630term | sbb-PD; Q1640term | sbb-PG; Q1630term | sbb-PH; Q1640term | sbb-PJ

Reported amino acid change:

Q1608term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(LaJeunesse et al., 2001)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Third instar larvae transheterozygous for sbb1/sbb324 or sbb324/sbb256 display a significant increase in turning rate during crawling, as compared to controls.

      (Suster et al., 2004)

      sbb270/sbb324 rare escapers have ectopic wing vein material.

      (LaJeunesse et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      sbb324 is an enhancer of partially lethal | recessive | male phenotype of Mer3

      (LaJeunesse et al., 2001)

      sbb324 is an enhancer of visible phenotype of MerΔBB.UAS.Tag:MYC, Scer\GAL4en-e16E

      (LaJeunesse et al., 2001)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      sbb4

      (LaJeunesse et al., 2001)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Allele strength (based on hemizygous lethal period): sbb270, sbb256, sbb151 > sbb324, sbb259.

      (LaJeunesse et al., 2001)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      IIa-bks324
      (LaJeunesse et al., 2001)
      sbb324
      (Suster et al., 2004)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)