FlyBase Allele Report: Dmel\lolal[311a]

General Information

Symbol

Dmel\lolal^311a

Species

D. melanogaster

Name

FlyBase ID

FBal0123781

Feature type

allele

Associated gene

Dmel\lolal

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Caused by aberration

Df(2R)lolal^311a

Cytology

Description

Proximal breakpoint of Df(2R)lolal^311a falls in the first intron of lolal thereby deleting the first exon and 5'region. The Df(2R)lolal^311a breaks are associated with the P{MTW}311a insertion.

(Faucheux et al., 2001)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Heteroallelic lolal^311a/lolal^k02512 flies have wild-type wings.

(Faucheux et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

lolal^311a is an enhancer of visible | homeotic phenotype of ph-p⁴¹⁰

(Faucheux et al., 2001)

Suppressor of

Statement

Reference

lolal^311a is a suppressor of visible | recessive | homeotic phenotype of Pc¹⁶

(Faucheux et al., 2003)

lolal^311a is a suppressor of visible | recessive | homeotic phenotype of ph-p⁴¹⁰

(Faucheux et al., 2003)

Phenotype Manifest In

Enhancer of

Statement

Reference

lolal^311a is an enhancer of sex comb phenotype of ph-p⁴¹⁰

(Faucheux et al., 2001)

Suppressor of

Statement

Reference

lolal^311a is a suppressor of mesothoracic leg phenotype of Pc¹⁶

(Faucheux et al., 2003)

lolal^311a is a suppressor of metathoracic leg phenotype of Pc¹⁶

(Faucheux et al., 2003)

lolal^311a is a suppressor of prothoracic leg | ectopic phenotype of Pc¹⁶

(Faucheux et al., 2003)

lolal^311a is a suppressor of mesothoracic leg phenotype of ph-p⁴¹⁰

(Faucheux et al., 2003)

lolal^311a is a suppressor of metathoracic leg phenotype of ph-p⁴¹⁰

(Faucheux et al., 2003)

lolal^311a is a suppressor of prothoracic leg | ectopic phenotype of ph-p⁴¹⁰

(Faucheux et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

A contrabithorax phenotype, which is a wing-to-haltere transformation due to ectopic expression of Ubx in the posterior part of the wing disc, often resulting in curvature of the wing, found in mutants heterozygous for lolal^k02512, lolal^k11212, or lolal^k07907, when also heterozygous for ph-p⁴¹⁰, Pc¹⁶, Pc¹, Pc³ or Pc¹⁵ is further enhanced in specific lolal heteroallelic viable combinations, such as lolal^k02512/lolal^311a, lolal^k11212/lolal^311a, and lolal^k07907/lolal^311a, when also heterozygous for ph-p⁴¹⁰, Pc¹⁶, Pc¹, Pc³ or Pc¹⁵.

(Faucheux et al., 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

lolal^311a is rescued by Scer\GAL4^da.G32/lolal^UAS.Tag:FLAG

(Faucheux et al., 2003)

lolal^311a is rescued by lolal^UAS.EGFP/Scer\GAL4^da.G32

(Faucheux et al., 2003)

lolal^311a is rescued by lolal^+tBB

(Faucheux et al., 2003)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Induced with: P{MTW}311a.

(Faucheux et al., 2001)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

ban^Df(2R)311a

(Faucheux et al., 2003)

lolal^311a

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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