FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\labUAS.cMa
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General Information
Symbol
Dmel\labUAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Miller
FlyBase ID
FBal0123782
Feature type
allele
Associated gene
Dmel\lab
Associated Insertion(s)
Carried in Construct
P{UAS-lab.M}
Also Known As
UAS-lab, UAS-labial
Key Links
Transgenic product class
cDNA
(Miller et al., 2001)
wild_type
(Miller et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Miller et al., 2001)
wild_type
(Miller et al., 2001)
Mutagen
in vitro construct
(Miller et al., 2001)
Progenitor genotype
Carried in construct
P{UAS-lab.M}
Cytology
Description

UASt sequences drive expression of a 2.1kb fragment of the lab cDNA.

(Miller et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
lab
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of labScer\UAS.cMa under the control of Scer\GAL4rn.PU suppresses wing formation.

      (Percival-Smith et al., 2013)

      When labScer\UAS.cMa is driven by Scer\GAL4sd-SG29.1 abnormal wing vein patterns and incisions in the wing margin are seen.

      (Adachi-Yamada et al., 2005)

      Expression of labScer\UAS.cMa under the control of Scer\GAL4sca-537.4 results in a mutant phenotype in the embryonic tritocerebrum. The phenotype has a penetrance of 25%.

      (Sprecher et al., 2004)

      When labScer\UAS.cMa is driven by Scer\GAL4how-24B, the normal pattern of muscle development is seen in the embryo. Midgut morphology is normal showing normal midgut constrictions and gastric caecae development.

      (Miller et al., 2001)

      When driven by Scer\GAL469B, Scer\GAL4prd.RG1, or Scer\GAL4l(3)31-1-31-1 leads to a significant loss in viability.

      (Miller et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4lab.PH/labUAS.cMa rescues lab14

      (Hirth et al., 2001)
      Comments

      Rescues the tritocerebral defects seen in lab14 embryos when expressed under the control of Scer\GAL4lab.PH.

      (Hirth et al., 2001)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      labScer\UAS.cMa
      labUAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Miller
      (Miller et al., 2001)
      Secondary FlyBase IDs
        References (18)