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General Information
Symbol
Dmel\UbxUAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Miller
FlyBase ID
FBal0123957
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Ubx
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt sequences drive expression of the Ubx NAB3 cDNA.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of UbxScer\UAS.cMa under the control of Scer\GAL4Vap.P0201 results in only 8% rescue of the cell death that is normally seen in anterior dMP2 neurons in late embryos. Expression of UbxScer\UAS.cMa under the control of Scer\GAL4elav-C155 only results in a marginal increase in survival of anterior dMP2 neurons in late embryos compared to wild-type embryos (where these neurons are lost by the late embryonic stage).

Expression of UbxScer\UAS.cMa under the control of Scer\GAL4sca-537.4 results in a mutant phenotype in the embryonic tritocerebrum. The phenotype has a penetrance of more than 95%.

Expression of UbxScer\UAS.cMa under the control of Scer\GAL4lab.PH does not result in morphological defects in the tritocerebrum or any other part of the embryonic brain.

When driven by Scer\GAL4how-24B, shows a clear transformation of posterior pharyngeal wall to an abdominal character. Two distinct rows of abdominal denticles are found on this structure. Prominent posterior central projections (PVs) are seen in the entire thorax indicating a partial transformation towards abdominal identity.

When driven by Scer\GAL469B, Scer\GAL4prd.RG1, or Scer\GAL4l(3)31-1-31-1 leads to a significant loss in viability.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Expression of UbxScer\UAS.cMa under the control of Scer\GAL4lab.PH rescues the tritocerebral defects seen in lab14 embryonic brains. 32.6% of embryos show a complete rescue of the defects (taking into account that the phenotypic penetrance of the lab14 phenotype is 88.6%).

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
UbxScer\UAS.cKa
UbxScer\UAS.cMa
UbxUAS.cKa
UbxUAS.cMa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Miller
Secondary FlyBase IDs
  • FBal0045262
References (10)