FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mPges2pe
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General Information
Symbol
Dmel\mPges2pe
Species
D. melanogaster
Name
FlyBase ID
FBal0123991
Feature type
allele
Associated gene
Dmel\mPges2
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Bichon et al., 2001)
Progenitor genotype
Cytology
Description

Amino acid replacement: T?S.

(Bichon et al., 2001)

The A2611C substitution and a 32bp insertion between nucleotides 2606 and 2607 (also found in Su(P)pr26) map towards the 3' end of the proposed Su(P) ORF.

(Bichon et al., 2001)

Nucleotide substitution: A2611C.

(Bichon et al., 2001)

Nucleotide substitution: T1438C.

(Bichon et al., 2001)

Nucleotide substitution: C1351G.

(Bichon et al., 2001)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
complex_substitution
3L:16,610,739..16,610,770 [-]
Comment:

32 base insertion. The Su(P)pe suppressor strain is reported as having a 32 base insertion as well as a A to C base change. Both are present in the reference genome.

(Bichon et al., 2001)
point_mutation
3L:16,612,026..16,612,026 [-]
Nucleotide change:

C16612026G

Reported nucleotide change:

C1351G

Amino acid change:

T31S | mPges2-PA

Reported amino acid change:

T?S

Comment:

The T to S amino acid change is reported in the Su(P)pe strain in addition to the 32 base insertion and the A to C nucleotide change, which are also present in Su(P)pr26. A silent nucleotide substitution as well as a couple of other sequence differences outside of the Su(P) gene are also reported.

(Bichon et al., 2001)
point_mutation
3L:16,610,735..16,610,735 [-]
Comment:

Site of A to C base change. The Su(P)pe suppressor strain is reported as having a 32 base insertion as well as a A to C base change. Both are present in the reference genome. At least one of these mutations is reported to be responsible for the difference between Su and non-Su alleles.

(Bichon et al., 2001)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      mPges2pe/Su(P)[+] is a suppressor of male sterile phenotype of ref(2)Pod3

      (Bichon et al., 2001)

      mPges2pe/Su(P)[+] is a suppressor of male sterile phenotype of ref(2)Pod2

      (Bichon et al., 2001)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Arose in: stock marked with p, e alleles.

      (Bichon et al., 2001)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Su(P)pe
      mPges2pe
      Name Synonyms
      Secondary FlyBase IDs
        References (1)