FB2026_02 , released June 18, 2026
Allele: Dmel\tsrUAS.Tag:polyHis
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General Information
Symbol
Dmel\tsrUAS.Tag:polyHis
Species
D. melanogaster
Name
FlyBase ID
FBal0128985
Feature type
allele
Associated gene
Dmel\tsr
Associated Insertion(s)
Carried in Construct
P{UAS-tsr.His}
Key Links
Transgenic product class
wild_type
(Niwa et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Niwa et al., 2002)
Mutagen
in vitro construct
(Niwa et al., 2002)
Progenitor genotype
Carried in construct
P{UAS-tsr.His}
Cytology
Description

UAS sequences drive expression of tsr tagged with Tag:polyHis.

(Niwa et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
tsr
Tagged with
Tag:polyHis
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  tauopathy
      modeled by Hsap\MAPTV337M.UAS
      (Fulga et al., 2007)
      ameliorates  Parkinson's disease 8
      modeled by Lrrke03680
      (Sarkar et al., 2021)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of tsrScer\UAS.T:Zzzz\His6 in flies expressing Hsap\MAPTV337M.Scer\UAS in the eye under the control of Scer\GAL4GMR.PF suppresses the rough-eye phenotype.

      Expression of tsrScer\UAS.T:Zzzz\His6 in animals expressing Hsap\MAPTR406W.Scer\UAS under the control of Scer\GAL4elav.PLu suppresses neuronal cell death.

      (Fulga et al., 2007)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in a plasmid and transfected into S2 cells to study its phosphorylation.

      (Niwa et al., 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      tsrScer\UAS.T:Zzzz\His6
      tsrUAS.Tag:polyHis
      Name Synonyms
      Secondary FlyBase IDs
        References (3)