FB2026_03 , released September 17, 2026
Allele: Dmel\CCT7KG01477
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General Information
Symbol
Dmel\CCT7KG01477
Species
D. melanogaster
Name
FlyBase ID
FBal0131372
Feature type
allele
Associated gene
Dmel\CCT7
Associated Insertion(s)
P{SUPor-P}CCT7KG01477
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{SUPor-P}CCT7KG01477
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{SUPor-P}
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  intrinsic cardiomyopathy
      CEA
      (Melkani et al., 2017)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      CCT7KG01477 homozygotes exhibit cardiac dysfunction under Light:Light or Light:Dark cycles, as shown by significant increases in heart period, arrhythmia, and diastolic and systolic intervals, and by small decreases in fractional shortening, and diastolic and systolic diameter, as compared to controls.

      (Melkani et al., 2017)

      In contrast to wild type, Tcp-1ηKG01477 mutant flies subjected to 12-hour daytime-restricted feeding (TRF) do not exhibit improved cardiac contractility relative to genotype and age-matched ad libitum feeding (ALF) flies, as measured by heart period and arrhythmicity.

      (Gill et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      CCT7KG01477 is an enhancer of visible | male phenotype of Pc11

      (Shaheen et al., 2021)

      CCT7KG01477 is an enhancer of visible | male phenotype of Pc1

      (Shaheen et al., 2021)

      CG8351[+]/CCT7KG01477 is an enhancer of visible phenotype of Df(1)os1

      (Mukherjee et al., 2006)
      Suppressor of
      Statement
      Reference

      CCT7KG01477 is a suppressor of homeotic | adult stage phenotype of trx1

      (Shaheen et al., 2021)

      CG8351[+]/CCT7KG01477 is a suppressor of visible phenotype of upd1GMR.PB

      (Mukherjee et al., 2006)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      CCT7KG01477 is an enhancer of sex comb phenotype of Pc11

      (Shaheen et al., 2021)

      CCT7KG01477 is an enhancer of sex comb phenotype of Pc1

      (Shaheen et al., 2021)

      CG8351[+]/CCT7KG01477 is an enhancer of eye phenotype of Df(1)os1

      (Mukherjee et al., 2006)
      Suppressor of
      Statement
      Reference

      CCT7KG01477 is a suppressor of adult abdominal segment phenotype of trx1

      (Shaheen et al., 2021)

      CG8351[+]/CCT7KG01477 is a suppressor of eye phenotype of upd1GMR.PB

      (Mukherjee et al., 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      CCT7KG01477
      (Shaheen et al., 2021)
      CG8351KG01477
      KG01477
      (Mukherjee et al., 2006)
      Tcp-1ηKG01477
      Name Synonyms
      Secondary FlyBase IDs
        References (5)