FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Cs1PG129
Open Close
General Information
Symbol
Dmel\Cs1PG129
Species
D. melanogaster
Name
FlyBase ID
FBal0131497
Feature type
allele
Associated gene
Dmel\Cs1
Associated Insertion(s)
P{GawB}Cs1PG129
Carried in Construct
Also Known As
PG129
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Bourbon et al., 2002)
Progenitor genotype
Associated Insertion(s)
P{GawB}Cs1PG129
Cytology
Description

Insertion within the large intron of kdn.

(Fergestad et al., 2006)

Re-mobilisation of the transposon causes the lethality phenotype to be lost.

(Bourbon et al., 2002)
Allele components
Component
Use(s)
Inserted element
P{GawB}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The giant fiber(GF)-dorsal longitudinal indirect flight muscle (DLM) neuronal circuit is more sensitive to seizure induction in kdnPC64/kdnPG129 mutants than in wild-type flies; seizures can be induced with high-frequency brain stimulation of shorter or less intensity in the mutant animals. The mutant animals show type I seizures.

      (Fergestad et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Cs1PC64

      (Fergestad et al., 2006)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Precise excision of the insertion reverts the lethal phenotype.

      (Fergestad et al., 2006)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      CG3861PG129
      (Bourbon et al., 2002)
      Cs1PG129
      kdnPG129
      l(1)G0030PG129
      Name Synonyms
      Secondary FlyBase IDs
        References (2)