FlyBase Allele Report: Dmel\mask[5.8]

General Information

Symbol

Dmel\mask^5.8

Species

D. melanogaster

Name

FlyBase ID

FBal0134056

Feature type

allele

Associated gene

Dmel\mask

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

loss of function allele

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

loss of function allele

(Smith et al., 2002)

Mutagen

ethyl methanesulfonate

(Smith et al., 2002)

Progenitor genotype

Cytology

Description

Amino acid replacement: Q3403term.

(Smith et al., 2002)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

3R:24,246,059..24,246,059 [+]

Nucleotide change:

C24246059T

Amino acid change:

Reported amino acid change:

Q3403term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Smith et al., 2002)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

mask^5.8 is an enhancer of visible phenotype of csw^CS.hs.2sev

(Smith et al., 2002)

Suppressor of

Statement

Reference

mask[+]/mask^5.8 is a suppressor of visible phenotype of csw^{hs.2sev.Tag:Myr(Src64B)}

(Smith et al., 2002)

mask[+]/mask^5.8 is a suppressor of visible phenotype of sev^S11.Tag:MYC

(Smith et al., 2002)

Phenotype Manifest In

Enhancer of

Statement

Reference

mask^5.8 is an enhancer of ommatidium phenotype of csw^CS.hs.2sev

(Smith et al., 2002)

Suppressor of

Statement

Reference

mask[+]/mask^5.8 is a suppressor of photoreceptor cell R7 | ectopic phenotype of csw^{hs.2sev.Tag:Myr(Src64B)}

(Smith et al., 2002)

mask[+]/mask^5.8 is a suppressor of photoreceptor cell R7 | ectopic phenotype of sev^S11.Tag:MYC

(Smith et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Enhances the csw^CS.hs.2sev rough eye phenotype. mask^5.8 dominantly suppresses the ectopic R7 phenotype caused by sev^{S11.T:Hsap\MYC}; the double mutant flies have an average of 1.9 ectopic R7 cells per ommatidium. mask^5.8 dominantly suppresses the ectopic R7 phenotype caused by csw::Src64B^hs.2sev; the double mutant flies have an average of 0.8 ectopic R7 cells per ommatidium.

(Smith et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

mask^5.8

(Sarkar et al., 2025, Sansores-Garcia et al., 2013)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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