FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mtdKG02600
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General Information
Symbol
Dmel\mtdKG02600
Species
D. melanogaster
Name
FlyBase ID
FBal0134062
Feature type
allele
Associated gene
Dmel\mtd
Associated Insertion(s)
P{SUPor-P}mtdKG02600
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Wang et al., 2013)
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{SUPor-P}mtdKG02600
Cytology
Description

Transcription of mtd-RC and all long transcripts (containing the TLDc and LysM domains) is reduced, whereas mtd-RH is unaffected.

(Wang et al., 2012)
Allele components
Component
Use(s)
Inserted element
P{SUPor-P}
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Compared with wild-type, mtde00435/mtdKG02600 mutants show increased sensitivity to H[[2]]O[[2]] ingestion.

      In the absence of infection, mtde00435/mtdKG02600 mutants have rates of intestinal stem cell division that is lower than those of control flies.

      (Wang et al., 2013)

      In contrast to mtdEY04695 flies, mtdf06038 mutants show increased susceptibility to V. cholerae infection.

      (Wang et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      KG02600
      (Wang et al., 2012)
      l(3)82FdKG02600
      mtdKG02600
      (Wang et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)