FB2026_02 , released June 18, 2026
Allele: Dmel\Pdk13
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General Information
Symbol
Dmel\Pdk13
Species
D. melanogaster
Name
FlyBase ID
FBal0135876
Feature type
allele
Associated gene
Dmel\Pdk1
Associated Insertion(s)
P{EP}EP837
Carried in Construct
Also Known As
EP837
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Rintelen et al., 2001)
Mutagen
ethyl methanesulfonate
(Rintelen et al., 2001)
P-element activity
(Rintelen et al., 2001)
Progenitor genotype
Pdk1EP837
(Rintelen et al., 2001)
Associated Insertion(s)
P{EP}EP837
Cytology
Description

Amino acid replacement: G352S.

(Rintelen et al., 2001)

The progenitor P{EP}Pdk1EP837 insertion is also still present.

(Rintelen et al., 2001)

Nucleotide substitution: G?A.

(Rintelen et al., 2001)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:142,117..142,117 [+]
Nucleotide change:

G142117A

Reported nucleotide change:

G?A

Amino acid change:

G309S | Pdk1-PA; G93S | Pdk1-PB; G373S | Pdk1-PC; G390S | Pdk1-PD; G93S | Pdk1-PE; G309S | Pdk1-PF; G93S | Pdk1-PG; G309S | Pdk1-PH; G390S | Pdk1-PJ

Reported amino acid change:

G352S

(Rintelen et al., 2001)
transposable_element_insertion_site
3L:131,762..131,762 [+]
(Rintelen et al., 2001)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The heads of mosaic flies with homozygous heads (generated using the "ey-FLP" system) are reduced in size.

      (Rintelen et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: a suppressor of the big eye phenotype caused by coexpression of Akt1Scer\UAS.cRa and Pk61CEP837 under the control of Scer\GAL4GMR.PF.

      (Rintelen et al., 2001)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Pdk13
      Pk61C3
      dPDK13
      (Rintelen et al., 2001)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)