FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\rgp2
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General Information
Symbol
Dmel\rgp2
Species
D. melanogaster
Name
FlyBase ID
FBal0138145
Feature type
allele
Associated gene
Dmel\rg
Associated Insertion(s)
P{lacW}rgp2
Carried in Construct
Key Links
Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Volders et al., 2012)
Mutagen
Delta2-3 transposase
(Shamloula et al., 2002)
Progenitor genotype
Associated Insertion(s)
P{lacW}rgp2
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  autism spectrum disorder
      CEA
      (Wise et al., 2015)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      rgp2 mutants display abnormal type I bouton morphology: changes in shape, fusion of boutons. Size of type I boutons remains unchanged.

      rgp6 mutant adults display decreased avoidance to a stress odorant.

      rgp6 mutant adults keep bigger distance from nearest neighbors.

      (Wise et al., 2015)

      Moderate rough eye phenotype.

      (Shamloula et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      rgγ6

      (Shamloula et al., 2002)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Excision of the P{lacW} element can revert the mutant eye phenotype.

      (Shamloula et al., 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      rgP2
      (Volders et al., 2012)
      rgp2
      (Wise et al., 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)