FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\rgγ6
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General Information
Symbol
Dmel\rgγ6
Species
D. melanogaster
Name
FlyBase ID
FBal0138151
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
Nature of the Allele
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

rgγ6 mutants display abnormal type I bouton morphology: changes in shape, fusion of boutons. Size of type I boutons remains unchanged but their number is significantly decreased.

rgγ6 mutants show increased habituation of the giant fiber circuit in adults.

Mutants have a rough eye phenotype. The ommatidia are irregular and not hexagonal in shape (in contrast to wild-type flies). The interommatidial bristles are irregularly positioned and multiple bristles are often found in place of the single bristle seen at each corner of the ommatidium in wild-type flies. The number of photoreceptor cells in each ommatidium is often abnormal and the precise position of the photoreceptor cells is also altered. The pigment cell lattice does not have a hexagonal arrangement, resulting in disorganisation of the retina. The photoreceptor cells which are missing from the ommatidia can be seen in the region below the fenestrated membrane. 20-40% of mutant fertilised eggs fail to hatch.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

rgγ6 has visible phenotype, enhanceable by Delta6B/Dl[+]

rgγ6 has visible phenotype, enhanceable by Egfr[+]/Egfrt1

rgγ6 has visible phenotype, enhanceable by Ras85DN17.hs.2sev

rgγ6 has visible phenotype, enhanceable by S54/S[+]

Suppressed by
Statement
Reference

rgγ6 has visible phenotype, suppressible by Egfr[+]/EgfrE1

rgγ6 has visible phenotype, suppressible by H[+]/HE31

rgγ6 has visible phenotype, suppressible | heat sensitive by Shs.30

Phenotype Manifest In
Enhanced by
Statement
Reference

rgγ6 has eye phenotype, enhanceable by Delta6B/Dl[+]

rgγ6 has eye phenotype, enhanceable by Egfr[+]/Egfrt1

rgγ6 has eye phenotype, enhanceable by Ras85DN17.hs.2sev

rgγ6 has eye phenotype, enhanceable by S54/S[+]

Suppressed by
Statement
Reference

rgγ6 has eye phenotype, suppressible by Egfr[+]/EgfrE1

rgγ6 has eye phenotype, suppressible by H[+]/HE31

rgγ6 has eye phenotype, suppressible | heat sensitive by Shs.30

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (3)