FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pygoUAS.cPa
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General Information
Symbol
Dmel\pygoUAS.cPa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Parker
FlyBase ID
FBal0138161
Feature type
allele
Associated gene
Dmel\pygo
Associated Insertion(s)
Carried in Construct
P{UAS-pygo.P}
Also Known As
UAS-pygo
Key Links
Transgenic product class
cDNA
(Parker et al., 2002)
wild_type
(Parker et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Parker et al., 2002)
wild_type
(Parker et al., 2002)
Mutagen
in vitro construct
(Parker et al., 2002)
Progenitor genotype
Carried in construct
P{UAS-pygo.P}
Cytology
Description

UASt sequences drive expression of a BglII/XhoI fragment of a pygo cDNA, which contains the entire 815 ORF and some 5' and 3' UTR sequences.

(Parker et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
pygo
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of pygoScer\UAS.cPa under the control of Scer\GAL4ptc-559.1 causes wing notches.

      (Bhambhani et al., 2011)

      Ectopic expression of pygoScer\UAS.cPa under the control of Scer\GAL430A prevent delamination of large portions of epithelium, and dorsal and ventral cuticle surfaces do not bond.

      (Kiger et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Phenotype Manifest In
      Suppressed by
      Suppressor of
      Statement
      Reference

      pygoUAS.cPa/Scer\GAL4GMR.PF is a suppressor of eye phenotype of Scer\GAL4GMR.PF, wgUAS.cKa

      (Parker et al., 2002)

      pygoUAS.cPa/Scer\GAL4GMR.PF is a suppressor of eye phenotype of armS56F.GMR

      (Parker et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of CtBPMono.Scer\UAS.T:Zzzz\FLAG with pygoScer\UAS.cPa under the control of Scer\GAL4ptc-559.1 significantly suppresses the loss of wing-margin caused by pygoScer\UAS.cPa-overexpression with a dramatic reduction in the frequency of big notches.

      (Bhambhani et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      pygoUAS.cPa/Scer\GAL4da.G32 partially rescues pygo10

      (Parker et al., 2002)
      Comments

      When pygoScer\UAS.cPa is added to maternal pygo10 mutants or maternal and zygotic pygo10 mutants and driven by Scer\GAL4da.G32, a significant rescue of the denticle belt phenotype is seen.

      (Parker et al., 2002)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      pygoScer\UAS.cPa
      pygoUAS.cPa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Parker
      (Parker et al., 2002)
      Secondary FlyBase IDs
        References (4)