FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\hfp9
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General Information
Symbol
Dmel\hfp9
Species
D. melanogaster
Name
FlyBase ID
FBal0138184
Feature type
allele
Associated gene
Dmel\hfp
Associated Insertion(s)
P{EP-Δ9}hfp9
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Van Buskirk and Schupbach, 2002)
Mutagen
P-element activity
(Van Buskirk and Schupbach, 2002)
Progenitor genotype
hfpEP3058
(Van Buskirk and Schupbach, 2002)
Associated Insertion(s)
P{EP-Δ9}hfp9
Cytology
Description

Internal deletion of the P{EP} element, with 481bp of the element remaining.

(Van Buskirk and Schupbach, 2002)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      24% of homozygous egg chambers contain only eight germline cells at room temperature. 96% of egg chambers have polytene nuclei and the karyosome appears abnormally shaped, diffuse or fragmented in 15.3% of egg chambers. Homozygous females lay few eggs, which are shorter than normal and have dorsal-ventral polarity defects (ranging from dorsalised with a ring of dorsal appendage material through to partially ventralised with a single dorsal appendage).

      (Van Buskirk and Schupbach, 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      hfp9 has karyosome phenotype, suppressible by otu104

      (Van Buskirk and Schupbach, 2002)

      hfp9 has nurse cell & nuclear chromosome phenotype, suppressible by otu104

      (Van Buskirk and Schupbach, 2002)

      hfp9 has egg chamber phenotype, suppressible by otu104

      (Van Buskirk and Schupbach, 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      otu104 rescues the nurse cell and oocyte nuclear morphology and germline division defects of pUf689 mutant females.

      (Van Buskirk and Schupbach, 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      hfp9 is rescued by hfpotu.GFP

      (Van Buskirk and Schupbach, 2002)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      hfp9
      (Casier et al., 2023, Blatt et al., 2021, Goodrich et al., 2004, Van Buskirk and Schupbach, 2002)
      pUf689
      Name Synonyms
      Secondary FlyBase IDs
        References (4)