FlyBase Allele Report: Dmel\sw[Dic-1]

General Information

Symbol

Dmel\sw^Dic-1

Species

D. melanogaster

Name

FlyBase ID

FBal0140915

Feature type

allele

Associated gene

Dmel\sw

Associated Insertion(s)

Carried in Construct

Also Known As

Dic¹

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Boylan and Hays, 2002)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of larval stage | recessive

(Boylan and Hays, 2002)

some die during larval stage | recessive

(Boylan and Hays, 2002)

visible (with sw¹)

(Boylan and Hays, 2002)

Phenotype Manifest In

axon | larval stage

(Nemtsova et al., 2023)

larval multidendritic neuron

(Nemtsova et al., 2023)

mitochondrion | larval stage

(Nemtsova et al., 2023)

wing (with sw¹)

(Boylan and Hays, 2002)

Detailed Description

Statement

Reference

Hemizygous lethality occurs predominantly at the larval stage.

(Boylan and Hays, 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

sw[+]/sw^Dic-1 is an enhancer of visible | dominant phenotype of DCTN1-p150^Gl-1

(Boylan and Hays, 2002)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

sw^Dic-1 has axon | larval stage phenotype, non-enhanceable by Sod1^G85R

(Nemtsova et al., 2023)

sw^Dic-1 has mitochondrion | larval stage phenotype, non-enhanceable by Sod1^G85R

(Nemtsova et al., 2023)

sw^Dic-1 has larval multidendritic neuron phenotype, non-enhanceable by Sod1^G85R

(Nemtsova et al., 2023)

NOT suppressed by

Statement

Reference

sw^Dic-1 has axon | larval stage phenotype, non-suppressible by Sod1^G85R

(Nemtsova et al., 2023)

sw^Dic-1 has mitochondrion | larval stage phenotype, non-suppressible by Sod1^G85R

(Nemtsova et al., 2023)

sw^Dic-1 has larval multidendritic neuron phenotype, non-suppressible by Sod1^G85R

(Nemtsova et al., 2023)

Enhancer of

Statement

Reference

sw[+]/sw^Dic-1 is an enhancer of ommatidium phenotype of DCTN1-p150^Gl-1

(Boylan and Hays, 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

sw^Dic-2

(Boylan and Hays, 2002)

sw^Dic-3

(Boylan and Hays, 2002)

sw¹

(Boylan and Hays, 2002)

Rescued by

sw^Dic-1 is rescued by sw^+t11

(Boylan and Hays, 2002)

sw¹/sw^Dic-1 is rescued by sw^+t11

(Boylan and Hays, 2002)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Dic¹

(Nemtsova et al., 2023, Boylan and Hays, 2002)

sw^Dic-1

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

Open Close