FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\fzre6
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General Information
Symbol
Dmel\fzre6
Species
D. melanogaster
Name
FlyBase ID
FBal0140965
Feature type
allele
Associated gene
Dmel\fzr
Associated Insertion(s)
Carried in Construct
Also Known As
rapE6
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Jacobs et al., 2002)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      rape6 third instar larvae show a significant increase in glia number compared to wild-type brains.

      (Kaplow et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      fzre6 has abnormal neuroanatomy | third instar larval stage phenotype, suppressible by loco[+]/locoP452

      (Kaplow et al., 2008)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      fzre6 has glial cell | ectopic | third instar larval stage phenotype, suppressible by loco[+]/locoP452

      (Kaplow et al., 2008)

      fzre6 has subperineurial glial cell | ectopic | third instar larval stage phenotype, suppressible by loco[+]/locoP452

      (Kaplow et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      A locoP452 heterozygous background is able to suppress the rape6 increased glial number phenotype.

      (Kaplow et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Allelic series in order of ascending strength rap1 < rape2 = rape4 = rape6, rapx-2 < rap3 = rapx-3.

      (Jacobs et al., 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      fzre6
      rapE6
      (Kaplow et al., 2008)
      rape6
      (Tanaka-Matakatsu et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)