FB2026_02 , released June 18, 2026
Allele: Dmel\oskM1R.fs(1)K10.3'UTR.UAS
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General Information
Symbol
Dmel\oskM1R.fs(1)K10.3'UTR.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0141008
Feature type
allele
Associated gene
Dmel\osk
Associated Insertion(s)
Carried in Construct
P{UAS-osk.M1R.K10.3'UTR}
Key Links
Transgenic product class
start_lost
(Vanzo and Ephrussi, 2002)
Mutagen
Nature of the Allele
Transgenic product class
start_lost
(Vanzo and Ephrussi, 2002)
Mutagen
in vitro construct
(Vanzo and Ephrussi, 2002)
Progenitor genotype
oskfs(1)K10.3'UTR.UAS
(Vanzo and Ephrussi, 2002)
Carried in construct
P{UAS-osk.M1R.K10.3'UTR}
Cytology
Description

Nucleotide substitution: A?C. Nucleotide substitution: T?G. Nucleotide substitution: G?C. Amino acid replacement: M1R. Only the short osk protein isoform is produced by this construct.

(Vanzo and Ephrussi, 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
osk
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos expressing oskM1R.fs(1)K10.3'UTR.Scer\UAS under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 develop anterior patterning defects, or even a bicaudal phenotype, in which anterior structures (head and thorax) are replaced by a duplicated abdomen of reversed polarity.

      (Suyama et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The anterior patterning defects observed in embryos expressing oskM1R.fs(1)K10.3'UTR.Scer\UAS under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 are significantly reduced in penetrance and severity in a Laspy41 background.

      (Suyama et al., 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      oskM1R.fs(1)K10.3'UTR.Scer\UAS
      oskM1R.fs(1)K10.3'UTR.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (4)