FB2026_02 , released June 18, 2026
Allele: Dmel\chicoPI3Kmut
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General Information
Symbol
Dmel\chicoPI3Kmut
Species
D. melanogaster
Name
FlyBase ID
FBal0144394
Feature type
allele
Associated gene
Dmel\chico
Associated Insertion(s)
Carried in Construct
P{chico.PI3Kmut}
Key Links
Transgenic product class
missense_variant
(Oldham et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Oldham et al., 2002)
Mutagen
in vitro construct
(Oldham et al., 2002)
Progenitor genotype
chico+t8
(Oldham et al., 2002)
Carried in construct
P{chico.PI3Kmut}
Cytology
Description

Construct: Amino acid replacement: Y411F. Amino acid replacement: Y641F.

(Oldham et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
chico
Encoded product / tool
chico
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      chicoPI3Kmut partially rescues chicounspecified

      (Oldham et al., 2002)
      Fails to rescue

      chicoPI3Kmut fails to rescue chico1

      (Oldham et al., 2002)
      Comments

      Fails to rescue the reduced body weight of chico loss of function mutants. Partially rescues the change in lipid accumulation of chico loss of function mutants. Fails to rescue the female sterility of chico1 mutants.

      (Oldham et al., 2002)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      chicoPI3Kmut
      Name Synonyms
      Secondary FlyBase IDs
        References (1)