FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Parp1hs.PU
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General Information
Symbol
Dmel\Parp1hs.PU
Species
D. melanogaster
Name
heat shock construct of Uchida
FlyBase ID
FBal0144694
Feature type
allele
Associated gene
Dmel\Parp1
Associated Insertion(s)
Carried in Construct
P{hs-Parp1.U}
Key Links
Transgenic product class
cDNA
(Uchida et al., 2002)
wild_type
(Uchida et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Uchida et al., 2002)
wild_type
(Uchida et al., 2002)
Mutagen
in vitro construct
(Uchida et al., 2002)
Progenitor genotype
Carried in construct
P{hs-Parp1.U}
Cytology
Description

A heat shock promoter drives expression of a full length Parp cDNA.

(Uchida et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
Parp1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Parphs.PU (using a 1 hour heat shock at 37oC every 12 hours from the early third instar to the end of the pupal stage) results in tissue polarity defects in the wing, notum, abdomen and eye. Expression of Parphs.PU (using heat shock of stage 12-13 embryos at 37oC for 2 hours) disrupts the organisation of the F-actin cytoskeleton of the epidermis.

      (Uchida et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Parp1hs.PU
      Parphs.PU
      Name Synonyms
      heat shock construct of Uchida
      (Uchida et al., 2002)
      Secondary FlyBase IDs
        References (1)